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5-Methylcytosine

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Definition: A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In PLANTS, the methylated sequence is CpNpGp, where N can be any base.      Other names Monohydrochloride, 5-Methylcytosine; 5 Methylcytosine Monohydrochloride; 5 Methylcytosine; 5-Methylcytosine Monohydrochloride
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N4-(2-(t-butyldisulfanyl)ethyl)-5-methylcytosine  0   5-Methylcytosine/*analogs & derivatives. Molecules. 2010;15(8) (dup#8):5692-707
5-methyl isocytosine  0   5-Methylcytosine/*analogs & derivatives. Biochemistry 2000 Aug 22;39(33):10177-88
5-methyldeoxycytosine  0   5-Methylcytosine/*analogs & derivatives. J Biol Chem 1990;265(27):16656
5-methyl-N(4)-hydroxycytosine  3171-25-3 2,4(1H,3H)-Pyrimidinedione, 5-methyl-, 4-oxime  5-Methylcytosine/*analogs & derivatives. Acta Biochim Pol 1980;27(1):57
1,5,N(4),N(4)-tetramethylcytosine  34171-45-4 2(1H)-Pyrimidinone, 4-(dimethylamino)-1,5-dimethyl  5-Methylcytosine/*analogs & derivatives. Biochim Biophys Acta 544(1):215;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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