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Thymine DNA Glycosylase

More information in Books or onNLM PubMed
Definition: An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.      Other names Glycosylase, Thymine Glycol; Glycosylase, Thymine DNA; Glycol Glycosylase, Thymine; G T Mismatch Specific Thymine DNA Glycosylase; DNA Glycosylase, Thymine; Thymine Glycol Glycosylase; Thymine Glycol DNA Glycosylase; G-T Mismatch-Specific Thymine DNA Glycosylase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
mismatch-specific thymine uracil-DNA glycosylase  EC 3.2.2.-   *Thymine DNA Glycosylase. Nature 1996 Oct 24;383(6602):735-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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