encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 
ψ 

GTP-Binding Protein alpha Subunits

More information in Books or onNLM PubMed
Definition: The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the heterotrimeric complex these subunits interact with a variety of second messenger systems. Hydrolysis of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The GTP-Binding protein alpha subunits are grouped into families according to the type of action they have on second messenger systems.     
Examples GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs 		Other names alpha Subunit, G-Protein; GTP Binding Protein alpha Subunits; GTP Binding Protein alpha Subunit; G Protein alpha Subunit; GTP-Binding Protein alpha Subunit; G-Protein alpha Subunit
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GPA-9 protein, C elegans  0   *Caenorhabditis elegans Proteins *GTP-Binding Protein alpha Subunits. Aging Cell 2011 Apr;10(2):208-19
GNA11 protein, human  0   *GTP-Binding Protein alpha Subunits. N Engl J Med. 2010 Dec 2;363(23):2191-9
GNAQ protein, human  0   *GTP-Binding Protein alpha Subunits. N Engl J Med. 2010 Dec 2;363(23):2191-9
gpa2 protein, S pombe  EC 3.6.5.1   *Schizosaccharomyces pombe Proteins *GTP-Binding Protein alpha Subunits.
Gnaz protein, mouse  0   *GTP-Binding Protein alpha Subunits.
Gnaz protein, rat  0   *GTP-Binding Protein alpha Subunits.
Gnat1 protein, mouse  0   *Transducin *GTP-Binding Protein alpha Subunits.
GasC protein, Penicillium marneffei  0   *GTP-Binding Protein alpha Subunits. Genetics 2003 Jun;164(2):487-99
GPA-16 protein, C elegans  EC 3.6.1.46   *Caenorhabditis elegans Proteins *GTP-Binding Protein alpha Subunits. Development 2003 Dec;130(23):5731-40
GPA1 protein, Arabidopsis  0   *Arabidopsis Proteins *GTP-Binding Protein alpha Subunits. Proc Natl Acad Sci U S A 1990 May;87(10):3821-5
magB protein, Magnaporthe grisea  0   *Fungal Proteins *GTP-Binding Protein alpha Subunits. Mol Plant Microbe Interact 2000 Nov;13(11) 1214-27
NtGA protein, Nicotiana tabacum  0   *Plant Proteins *GTP-Binding Protein alpha Subunits. Genes Genet Syst 2000 Aug;75(4):211-21
GNA-3 protein, Neurospora crassa  0   *Fungal Proteins *GTP-Binding Protein alpha Subunits. Mol Cell Biol 2000 Oct;20(20):7693-705
Gpa3 protein, Ustilago maydis  0   *Fungal Proteins *GTP-Binding Protein alpha Subunits. EMBO J 1997 Apr 15;16(8):1934-42
Gpa4 protein, Ustilago maydis  0   *Fungal Proteins *GTP-Binding Protein alpha Subunits. EMBO J 1997 Apr 15;16(8):1934-42
GNAZ protein, human  0   *GTP-Binding Protein alpha Subunits. J Biol Chem 1989 Sep 5;264(25):14960-4; J Biol Chem 1990 Feb 5;265(4):2383-90
Galpha5 protein, Dictyostelium  0   *Protozoan Proteins *GTP-Binding Protein alpha Subunits. Development 1996 Apr;122(4):1215-24
olfactory G protein subunit alpha olf  0   *GTP-Binding Protein alpha Subunits. Endocrinology 1993 Dec;133(6):2508-14
Gpa2 protein, S cerevisiae  EC 3.6.5.1   *Saccharomyces cerevisiae Proteins *GTP-Binding Protein alpha Subunits. Genes Dev 1992 Dec;6(12B):2455-62

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy