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Alkane 1-Monooxygenase

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Definition: A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as octane and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS.      Other names P-450 IVA, Cytochrome; P-450 CYP4A, Cytochrome; P-450 4A, Cytochrome; Omega-hydroxylase, Lauric Acid; Omega-Hydroxylase, Laurate; Omega-Hydroxylase, Fatty Acid; Omega Lauryl Hydroxylase; Omega Hydroxylase; Omega 1 Hydroxylase; Lauric Acid Omega hydroxylase; Laurate Omega Hydroxylase; Hydroxylase, Omega-Lauryl; Hydroxylase, Omega-1; Hydroxylase, Alkane; Fatty Acid Omega Hydroxylase; Cytochrome P 450 IVA; Cytochrome P 450 CYP4A; Cytochrome P 450 4A; CYP4A, Cytochrome P-450; Alkane 1 Monooxygenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Cyp4d21 protein, Drosophila  EC 1.14.15.3   *Drosophila Proteins *Alkane 1-Monooxygenase. Genetics 2008 Sep;180(1):179-90
cytochrome P-450 96A15, Arabidopsis  EC 1.14.15.3   *Arabidopsis Proteins *Alkane 1-Monooxygenase. Plant Physiol 2007 Nov;145(3):653-67

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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