Definition: A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
see SCR for organism-specific terms
Other names Tyrosine Kinase, TIE2; Tie-2, Angiopoietin Receptor; TIE-2 Receptor; TIE 2 Receptor Tyrosine Kinase; Receptor, Tie2; Receptor, Tek; Receptor, TIE 2; Receptor Tie-2, Angiopoietin; Angiopoietin Receptor Tie 2; Tie2 Receptor; Tek Receptor; TIE2 Tyrosine Kinase; Angiopoietin Receptor Tie-2; TIE-2-RTK; TIE-2 Receptor Tyrosine Kinase
