Definition: The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.
Other names Collapsin 1; Semaphorin D; Semaphorin 3A; Sema3A; Collapsing Factor; Collapsin-1; Collapsin; Sem D
