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Integrin beta Chains

More information in Books or onNLM PubMed
Definition: Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.     
Examples Antigens, CD18; Antigens, CD29; Integrin beta3; Integrin beta4 		Other names beta Chains, Integrin; Integrins, beta; Integrin beta Subunits; beta Integrins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bint1 protein, Anopheles  0   *Insect Proteins *Integrin beta Chains. Insect Mol Biol 2001 Jun;10(3):217-23
integrin betaL, Strongylocentrotus purpuratus  0   *Integrin beta Chains. Dev Biol 1998 Nov 1;203(1):134-48
betaG integrin, Strongylocentrotus purpuratus  0   *Integrin beta Chains. Dev Biol 1997 Jan 15;181(2):234-45
integrin beta8  0   *Integrin beta Chains. Mol Biol Cell 1995 Apr;6(4):419-31
pat-3 protein, C elegans  0   *Caenorhabditis elegans Proteins *Integrin beta Chains. J Cell Biol 1995 May;129(4):925-37
integrin beta7  0   *Integrin beta Chains. Am J Pathol 1991 Dec;139(6):1297-301
integrin betanu, Drosophila  153552-93-3   *Drosophila Proteins *Integrin beta Chains. Development 1993 Jul;118(3):845-58
integrin beta5  0   *Integrin beta Chains. Gene 1993 Nov 15;133(2):307-8
integrin beta6  0   *Integrin beta Chains. Immunogenetics 1992;35(1)58

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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