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Cleavage Stimulation Factor

More information in Books or onNLM PubMed
Definition: A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.      Other names CstF Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CstF-77 protein, human  0   *Cleavage Stimulation Factor. Nature 1994 Dec 1;372(6505):471-4
CstF64 protein, Arabidopsis  0   *Arabidopsis Proteins *Cleavage Stimulation Factor. Science. 2010 Jan 1;327(5961):94-7
CstF77 protein, Arabidopsis  0   *Arabidopsis Proteins *Cleavage Stimulation Factor. Protein Pept Lett 2008;15(1):76-88
CstF-77 protein, mouse  0   *Cleavage Stimulation Factor. Mol Cell 2007 Mar 23;25(6):863-75
CstF-77 protein, Xenopus  0   *Xenopus Proteins *Cleavage Stimulation Factor Protein Subunits. J Biol Chem 2006 Sep 29;281(39):28687-98
CstF-64 protein, rat  0   *Cleavage Stimulation Factor. Biol Reprod 2004 Apr;70(4):1080-7
Cstf2t protein, mouse  0   *Cleavage Stimulation Factor. Biol Reprod 2004 Apr;70(4):1080-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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