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Follistatin

More information in Books or onNLM PubMed
Definition: A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.      Other names Activin Binding Protein; Activin-Binding Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FS I-I protein  0   *Recombinant Fusion Proteins Follistatin. FASEB J 2008 Feb;22(2):477-87
FST protein, human  0   *Follistatin.
follistatin, 288-amino acid isoform  0   *Follistatin. Hepatology 2003 Nov;38(5):1107-15

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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