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Cyclic ADP-Ribose

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Definition: A pyridine nucleotide that mobilizes CALCIUM. It is synthesized from nicotinamide adenine dinucleotide (NAD) by ADP RIBOSE CYCLASE.      Other names cADP Ribose; Cyclic ADP Ribose; ADPribose, Cyclic; ADP-Ribose, Cyclic; Cyclic Adenosine Diphosphate Ribose; Cyclic ADPribose; cADPR; cADP-Ribose; Adenosine Diphosphate Ribose, Cyclic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
8-trifluoromethyl-N1-((5''-O-phosphorylethoxy)methyl)-5'-O-phosphorylinosine-5',5''-cyclic pyrophosphate  0   Cyclic ADP-Ribose/*analogs & derivatives. Org Biomol chem 2010 Oct 21;8(20):4705-15
3''-deoxy-cyclic ADP-carbocyclic-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2006;25(4-6):583-99
cyclic ADP-carbocyclic-xylose  0   Cyclic ADP-Ribose/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2006;25(4-6):583-99
methylenebisphosphonate cyclic 3-deaza-ADP-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. J Med Chem 2005 Jun 16;48(12):4177-81
methylenebisphosphonate cyclic ADP-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. J Med Chem 2005 Jun 16;48(12):4177-81
8-bromo-cyclic-ADP-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. Microvasc Res 2004 Mar;67(2):159-67
cyclic ADP-carbocyclic-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. J Am Chem Soc 2001 Sep 12;123(36):8750-9
8-methoxy cyclic adenosine 5'-diphosphate ribose  0   Cyclic ADP-Ribose/*antagonists & inhibitors. Br J Pharmacol 1999 Nov;128(6):1235-40
7-deaza-8-bromo-cyclic ADP-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. J Biol Chem 1997 Jun 27;272(26):16358-63
7-deaza cyclic adenosine 5'-diphosphate ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. Chem Biol 1997 Jan;4(1):51-61
cyclic ADP-ribose 2'-phosphate  0   Cyclic ADP-Ribose/*analogs & derivatives. J Biol Chem 1996 Mar 1;271(9):4747-54
cyclic aristeromycin diphosphate ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. FEBS Lett 1996 Feb 5;379(3):227-30
caged cyclic ADP-ribose  0   Cyclic ADP-Ribose/*analogs & derivatives. J Biol Chem 1995 Mar 31;270(13):7745-9
8-azido-cyclic adenosine diphosphate ribose  150424-94-5   Cyclic ADP-Ribose/*antagonists & inhibitors. J Biol Chem 1993 Dec 15;268(35):26686-91
8-aminoadenosine cyclic 3',5'-(hydrogen phosphate) 5'-ribofuranosyl ester  151898-25-8   Cyclic ADP-Ribose/*analogs & derivatives. Science 1993 Jul 16;261(5119):352-5

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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