Definition: A class of proteins related in structure and function to TATA-BOX BINDING PROTEIN that can take the place of TATA-BOX BINDING PROTEIN in the transcription initiation complex. They are found in most multicellular organisms and may be involved in tissue-specific promoter regulation. They bind to DNA and interact with TATA-BINDING PROTEIN ASSOCIATED FACTORS, however they may lack specificity for the TATA-BOX.
X ref TBP-RELATED FACTOR: see SCR for organism-specific TBP-related factors
Other names TLP, TBP-Like; TBP Related Factor; TBP Like TLP; TATA Box Binding Protein Like Proteins; TATA Binding Protein Related Factors; TATA Binding Protein Related Factor; TBP-Like TLP; TBP-Like Protein (TLP); TATA-Binding Protein-Related Factors; TATA-Binding Protein-Related Factor; TBP-Related Factor
