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MADS Domain Proteins

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Definition: A superfamily of proteins that share a highly conserved MADS domain sequence motif. The term MADS refers to the first four members which were MCM1 PROTEIN; AGAMOUS 1 PROTEIN; DEFICIENS PROTEIN; and SERUM RESPONSE FACTOR. Many MADS domain proteins have been found in species from all eukaryotic kingdoms. They play an important role in development, especially in plants where they have an important role in flower development.  note X refs; AGAMOUS PROTEIN, ARABIDOPSIS and DEFICIENS PROTEIN are also available   
Examples AGAMOUS Protein, Arabidopsis; DEFICIENS Protein; Serum Response Factor
Other names Proteins, Agamous-Related; Deficiens Agamous Related Proteins; Deficiens Agamous Like Proteins; Agamous Related Proteins; Agamous Like Proteins; Deficiens-Agamous-Related Proteins; Agamous-Related Proteins; Deficiens-Agamous-Like Proteins; Agamous-Like Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AGL36 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. PLoS Genet 2011 Feb;7(2):e1001303
AGL61 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Physiol 2008 Sep;148(1):259-68
AGL17 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Cell 1995 Aug;7(8):1259-69
MEF2A protein, rat  0   *Myogenic Regulatory Factors *MADS Domain Proteins. Am J Physiol Endocrinol Metab 2008 Sep;295(3):E698-704
XAL1 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Physiology 2008 Mar;146(3):1182-92
FLM protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant J 2007 Jun;50(6):1049-62
AGL18 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant J 2007 Jun;50(6):1007-19
AGL15 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Cell 1995 Aug;7(8):1271-82
MEF2 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins MADS Domain Proteins. Dev Biol 2000 Jul 15;223(2):431-40
UNC-120 protein, C elegans  0   *MADS Domain Proteins *Caenorhabditis elegans Proteins. Genes Dev 2006 Dec 15;20(24):3342-6
AGAMOUS-LIKE 28 protein,, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Biochem Biophys Res Commun 2006 Sep 29;348(3):929-36
AGL19 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant J 2000 Nov;24(4):457-66
MEF2D protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
MEF2C protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
MEF2B protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
MEF2A protein, human  0   *Myogenic Regulatory Factors *MADS Domain Proteins.
flowering locus D protein, Arabidopsis  EC 3.5.1.-   *Histone Deacetylases *MADS Domain Proteins *Arabidopsis Proteins Repressor Proteins. Science 2003 Dec 5;302(5651):1751-4
AGL24 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Cell Physiol 2003 Jul;44(7):735-42
SEEDSTICK protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Nature 2003 Jul 3;424(6944);85-8
PHERES1 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Genes Dev 2003 Jun 15;17(12):1540-53
TT16 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Cell 2002 Oct;14(10):2463-79
AGL21 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Planta 2002 Jan;214(3):365-72
ERAF17 protein, Cucumis sativus L  0   *Plant Proteins *MADS Domain Proteins. Planta 2001 Oct;213(6):943-52
CanMADS1 protein, Capsicum annuum  0   *Plant Proteins *MADS Domain Proteins. Mol Cells 2001 Jun 30;11(3):352-9
CanMADS6 protein, Capsicum annuum  0   *Plant Proteins *MADS Domain Proteins. Mol Cells 2001 Jun 30;11(3):352-9
DEFH28 protein, Antirrhinum majus  0   *Plant Proteins *MADS Domain Proteins. Plant J 2001 Oct;28(2):169-79
ZMM2 protein, Zea mays  0   *Plant Proteins *MADS Domain Proteins.
AGL20 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins.
SHP2 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins.
SHP1 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins.
POTM1-1 protein, Solanum tuberosum  0   *Plant Proteins *MADS Domain Proteins.
FBP9 protein, Petunia hybrida  0   *Plant Proteins *MADS Domain Proteins.
AGAMOUS-like protein 2, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins.
AGAMOUS-like protein 1, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins Arabidopsis.
FLF protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins.
J protein, Lycopersicon esculentum  0   *Plant Proteins *MADS Domain Proteins. Mol Gen Genet 1994 Mar;242(6):681-8
CUM protein, Cucumis sativus  0   *Plant Proteins *MADS Domain Proteins. Plant Cell 1998 Feb;10(2):171-82
APETALA 3 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Cell 1992 Feb 21;68(4):683-97
ZAG5 protein, Zea mays  0   *Plant Proteins *MADS Domain Proteins. Plant J 1995 Dec;8(6):845-54
ZAG4 protein, Zea mays  0   *Plant Proteins *MADS Domain Proteins. Plant J 1995 Dec;8(6):845-54
ZAG3 protein, Zea mays  0   *Plant Proteins *MADS Domain Proteins. Plant J 1995 Dec;8(6):845-54
AGL8 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Plant Cell 1995 Nov;7(11):1763-71
RLM1 protein, S cerevisiae  0   *MADS Domain Proteins *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1995 Oct;15(10):5740-9
ZEM protein, Zea mays  169440-91-9   *Plant Proteins *MADS Domain Proteins. Nucleic Acids Res 1995 Jun 25:23(12):2168-77
CAL protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Science 1995 Jan 27;267(5197):522-5
AP1 protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Science 1995 Jan 27;267(5197):522-5
PISTILLATA protein, Arabidopsis  0   *MADS Domain Proteins *Arabidopsis Proteins. Genes Dev 1994 Jul 1;8(13):1548-60
TobMADS1 protein, Nicotiana tabacum  0   *Plant Proteins *MADS Domain Proteins. Plant Mol Biol 1994 May;25(2):319-21
PMADS 2 protein, Petunia hybrida  0   *Plant Proteins *MADS Domain Proteins. Plant Physiol 1993 Jul;102(3):1051-2
GP protein, Petunia x hybrida  0   *Plant Proteins *MADS Domain Proteins. Plant Physiol 1993 Jul;102(3):1051-2
ZAG2 protein, Zea mays  0   *Plant Proteins *MADS Domain Proteins. Plant Cell 1993 Jul;5(7):729-37
ZAG1 protein, Zea mays  0   *Plant Proteins *MADS Domain Proteins. Plant Cell 1993 Jul;5(7):729-37
PLE protein, Antirrhinum majus  0   *Plant Proteins *MADS Domain Proteins. Cell 1993 Jan 15;72(1):85-95
fbp2 protein, Petunia x hybrida  147276-31-1   *Plant Proteins *MADS Domain Proteins. Plant Cell 1992 Aug:4(8):983-93
fbp1 protein, Petunia x hybrida  147276-30-0   *Plant Proteins *MADS Domain Proteins. Plant Cell 1992 Aug;4(8):983-93

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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