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alpha-Defensins

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Definition: DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.     
Pharmacological Action Anti-Infective Agents 		Other names alpha Defensins; Peptides, Neutrophil Antimicrobial; Neutrophil Antimicrobial Peptides; Antimicrobial Peptides, Neutrophil
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
alpha-defensin 6, human  0   *alpha-Defensins. Protein Sci 2006 Dec;15(12):2749-60
alpha-defensin 5, human  0   *alpha-Defensins. J Biol Chem 1992 Nov 15;267(32):23216-25
neutrophil peptide 3, rat  0   *alpha-Defensins. J Leukoc Biol 2004 Feb;75(2):332-41
NP-1 protein, Oryctolagus cuniculus  0   *alpha-Defensins. Curr Genet 2001 Jul;39(5-6):365-70
DEFA1A3 protein, human  0   *Peptides, Cyclic *alpha-Defensins. Biochemistry 2001 Apr 10;40(14):4211-21
defensin NP-3a  0   *alpha-Defensins.
defensin NP-1  0   *alpha-Defensins.
neutrophil peptide 5  0   *alpha-Defensins.
human neutrophil peptide 4  0   *alpha-Defensins.
human neutrophil peptide 3  0   *alpha-Defensins.
human neutrophil peptide 2  0   *alpha-Defensins.
human neutrophil peptide 1  0   *alpha-Defensins.
Pharma Action Anti-Infective Agents
RK-1 peptide  0   *alpha-Defensins. J Pept Sci 2000 Jan;6(1):19-25
cryptdin 4, mouse  0   *alpha-Defensins Anti-Infective Agents. Infect Immun 1999 Dec;67(12):6643-51

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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