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Receptors, Interleukin-8B
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Definition
: High-affinity G-protein-coupled receptors for INTERLEUKIN-8 present on NEUTROPHILS; MONOCYTES; and T-LYMPHOCYTES. These receptors also bind several other CXC CHEMOKINES.
DF: IL8RB
Other names
Receptors, Interleukin 8B; Receptor, Interleukin-
8B; Interleukin 8B Receptors; Interleukin 8B Receptor; Interleukin 8 Receptors Type B; Interleukin 8 Receptors B; Interleukin 8 Receptor Type B; Interleukin-
8B Receptor; Interleukin-
8 Receptors Type B; Interleukin-
8 Receptors B; Interleukin-
8 Receptor Type B; Receptors, CXCR2; Interleukin-
8B Receptors; CXCR2 Receptors; CXCR2 Protein; CXC Chemokine Receptor 2; CDw128b Antigens; Antigens, CDw128b
Substance
CAS Registry & name
Categories
Source
Drugs
*
SB 656933
0
*Phenylurea Compounds
*Sulfonamides
Receptors, Interleukin-8B/antagonists & inhibitors.
Br J Clin Pharmacol. 2011 Aug;72(2):282-93.
1-
(2-
bromophenyl)-
3-
(7-
cyano-
3H-
benzotriazol-
4-
yl)urea
0
*Triazoles
*Phenylurea Compounds
Receptors, Interleukin-8B.
Br J Pharmacol 2009 Sep;158(1):328-38
SCH 479833
0
*Benzamides
*Cyclobutanes
Receptors, Interleukin-8A/antagonists & inhibitors
Receptors, Interleukin-8B/antagonists & inhibitors.
Clin Cancer Res 2009 Apr 1;15(7):2380-6
4-
(2-
amino-
1-
methyl-
2-
oxoethyl)phenyl trifluoromethanesulfonate
0
*Mesylates
*Benzeneacetamides
Receptors, Interleukin-8A/antagonists & inhibitors
Receptors, Interleukin-8B/antagonists & inhibitors.
Br J Pharmacol 2008 Mar;153(5):992-1002
4-
(1-
methyl-
2-
oxo-
2-
((4-
(trifluoromethyl)-
1,3-
thiazol-
2-
yl)amino)ethyl)phenyl trifluoromethanesulfonate
0
*Mesylates
*Phenylpropionates
Receptors, Interleukin-8A/antagonists & inhibitors
Receptors, Interleukin-8B/antagonists & inhibitors.
J Med Chem 2007 Aug 23;50(17):3984-4002
2-
((4-
trifluoromethylsulfonyloxy)phenyl)propanamide
0
*Mesylates
*Phenylpropionates
Receptors, Interleukin-8A/antagonists & inhibitors
Receptors, Interleukin-8B/antagonists & inhibitors.
J Med Chem 2007 Aug 23;50(17):3984-4002
2-
(4-
(trifluoromethylsulfonyloxy)phenyl)propanoic acid
0
*Mesylates
*Phenylpropionates
Receptors, Interleukin-8A/antagonists & inhibitors
Receptors, Interleukin-8B/antagonists & inhibitors.
J Med Chem 2007 Aug 23;50(17):3984-4002
2-
hydroxy-
N,N-
dimethyl-
3-
(2-
((1-
(5-
methylfuran-
2-
yl)propyl)amino)-
3,4-
dioxocyclobut-
1-
enylamino)benzamide
0
*Benzamides
*Cyclobutanes
Receptors, Interleukin-8A/antagonists & inhibitors
Receptors, Interleukin-8B/antagonists & inhibitors.
J Med Chem 2006 Dec 28;49(26):7603-6
N-
(3-
bromo-
4-
cyano-
2-
hydroxyphenyl)-
N'-
(2-
bromophenyl)urea
0
*Phenylurea Compounds
Receptors, Interleukin-8B/antagonists & inhibitors.
J Med Chem 2004 Mar 11;47(6):1319-21