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omega-Agatoxin IVA

More information in Books or onNLM PubMed
Definition: A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.     
Pharmacological Action Calcium Channel Blockers; Neurotoxins
Other names omega Agatoxin IVA; omega Aga IVA; IVA, omega-Agatoxin; omega-Aga-IVA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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