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Plasma Kallikrein
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Definition
: A peptidohydrolytic enzyme that is formed from PREKALLIKREIN by FACTOR XIIA. It activates FACTOR XII; FACTOR VII; and PLASMINOGEN. It is selective for both ARGININE and to a lesser extent LYSINE bonds. EC 3.4.21.34.
Pharmacological Action
Coagulants
Other names
Kallikrein, Serum; Kallikrein, Plasma; Serum Kallikrein; Kininogenin; Kallikrein I
Substance
CAS Registry & name
Categories
Source
Drugs
*
PF 04886847
0
*Aminobenzoic Acids
*Aminopyridines
Plasma Kallikrein/antagonists & inhibitors.
Br J Pharmacol 2011 Apr;162(7):1639-49