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I-kappa B Proteins

More information in Books or onNLM PubMed
Definition: A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.     
See Also I-kappa B Kinase; NF-kappa B; Proto-Oncogene Proteins c-rel
Other names IkB DNA Binding Proteins; I kappa B Proteins; IkB DNA-Binding Proteins; I-kappa B; I kappa B
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
IkappaBeta protein, mouse  0   *I-kappa B Proteins. Proc Natl Acad Sci U S A 2010 Jun 29;107(26):11924-9
Nfkbie protein, mouse  0   *Proto-Oncogene Proteins *I-kappa B Proteins.
AL 366 protein, human  0   *Glycoproteins *I-kappa B Proteins I-kappa B Proteins. Amyloid 2001;8(2):111-4
NFKBIE protein, human  0   *Proto-Oncogene Proteins *I-kappa B Proteins. EMBO J 1997 Mar 17;16(6):1413-26
I kappa B beta protein  0   *I-kappa B Proteins NF-kappa B/antagonists & inhibitors. Nucleic Acids Res 1992 Feb 11;20(3):607
NF-kappaB inhibitor alpha  139874-52-5   *I-kappa B Proteins NF-kappa B/antagonists & inhibitors. Cell 1991;65(7):1281

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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