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GTP-Binding Protein Regulators

More information in Books or onNLM PubMed
Definition: Proteins that regulate the signaling activity of GTP-BINDING PROTEINS. They are divided into three categories depending upon whether they stimulate GTPase activity (GTPASE-ACTIVATING PROTEINS), inhibit release of GDP; (GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS).  Do not confuse with RGS proteins; DF: GTP BINDING PROTEIN REG   
Examples GTPase-Activating Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanine Nucleotide Exchange Factors 		Other names Signaling Regulators, G-Protein; Regulators, GTP-Binding Protein; Regulators, G Protein Signaling; Regulating Factors, GTP Binding Protein; GTP Binding Protein Regulators; G Protein Signaling Regulators; G Protein Regulating Factors; Regulating Factors, GTP-Binding Protein; Regulating Factors, G-Protein; Regulators, G-Protein Signaling; G-Protein Signaling Regulators; G-Protein Regulating Factors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
regulator of G-protein signaling 22, human  0   *Antigens, Surface *GTP-Binding Protein Regulators. Biol Reprod 2008 Dec;79(6):1021-9
Jpk protein, mouse  0   *GTP-Binding Protein Regulators Apoptosis. Ann N Y Acad Sci. 2006 Dec;1090():182-7
RGS21 protein, human  0   *GTP-Binding Protein Regulators. Acta Biochim Pol 2005;52(4):943-6
Rgs21 protein, rat  0   *GTP-Binding Protein Regulators. Eur J Neurosci. 2004 Mar;19(6):1535-44
CDC42EP5 protein, human  0   *GTP-Binding Protein Regulators cdc42 GTP-Binding Protein.
CDC42EP3 protein, human  0   *GTP-Binding Protein Regulators cdc42 GTP-Binding Protein.
Cdc42ep5 protein, mouse  0   *GTP-Binding Protein Regulators cdc42 GTP-Binding Protein.
CDC42EP4 protein, human  0   *GTP-Binding Protein Regulators cdc42 GTP-Binding Protein. J Biol Chem 2001 Jan 12;276(2):875-83
CDC42EP2 protein, human  0   *GTP-Binding Protein Regulators GTP Phosphohydrolase Activators. J Biol Chem 2001 Jan 12;276(2):875-83
SRP101 protein, Yarrowia lipolytica  0   *Fungal Proteins *Receptors, Peptide *GTP-Binding Protein Regulators. Yeast 2000 Sep 30;16(13):1243-52
EAT-16 protein, C elegans  0   *GTP-Binding Protein Regulators *Caenorhabditis elegans Proteins. Genes Dev 1999 Jul 15;13(14):1780-93
phosducin  0   *Eye Proteins *Phosphoproteins *GTP-Binding Protein Regulators Protein Kinases. J Biol Chem 1990;265(26):15860

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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