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Inhibitory Concentration 50

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Definition: The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.  do not confuse with LETHAL DOSE 50, determined in animals   
See Also Microbial Sensitivity Tests
Other names Concentration 50, Inhibitory; 50, Inhibitory Concentration; IC50

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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