Definition: An arylsulfatase that catalyzes the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux-Lamy syndrome (MUCOPOLYSACCHARIDOSIS VI). EC 3.1.6.12.
Other names Sulphatase, N-Acetylgalactosamine-4-sulphate; Sulfatase, N-Acetylgalactosamine-4-sulfate; N Acetylgalactosamine 4 sulphate Sulphatase; N Acetylgalactosamine 4 sulfate Sulfatase; N Acetylgalactosamine 4 Sulfatase; B2, Arylsulfatase; B1, Arylsulfatase; B, Arylsulfatase; 4-Sulfatase, N-Acetylgalactosamine; N-Acetylgalactosamine-4-sulphate Sulphatase; N-Acetylgalactosamine-4-sulfate Sulfatase; N-Acetylgalactosamine 4-Sulfatase; Arylsulfatase B2; Arylsulfatase B1; Arylsulfatase B
