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Cyclin-Dependent Kinase Inhibitor p16

More information in Books or onNLM PubMed
Definition: A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.     
See Also Genes, p16; Tumor Suppressor Protein p14ARF 		Other names Protein, INK4A; Multiple Tumor Suppressor 1; Cyclin Dependent Kinase Inhibitor p16; Cyclin Dependent Kinase Inhibitor 2A; Cdk4 Associated Protein p16; p16INK4A Protein; p16INK4 Protein; p16(INK4A); Multiple Tumor Suppressor-1; MTS1 Protein; INK4A Protein; Cyclin-Dependent Kinase Inhibitor-2A; Cdk4-Associated Protein p16; CDKN2A Protein; CDKN2 Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Cdkn2a protein, mouse  0   *Cyclin-Dependent Kinase Inhibitor p16 Genes, p16.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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