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Genomic Imprinting

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Definition: The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)     
See Also DNA Methylation 		Other names Parental Imprinting; Genetic Imprinting; Imprinting, Parental; Imprinting, Genomic; Imprinting, Genetic
 
SubstanceCAS Registry & nameCategoriesSource
Sfmbt2 protein, mouse  0   *Transcription Factors Genomic Imprinting. Gene Expr Patterns. 2008 Jan;8(2):107-16
TSSC3 protein  0   *Nuclear Proteins Placenta Liver Genes, Tumor Suppressor Genomic Imprinting. Genomics 1997 Nov 15;46(1):9-17; Hum Mol Genet 1997 Nov;6(12):2021-9
H19 long non-coding RNA  0   *RNA, Untranslated Genomic Imprinting. Cell Growth Differ 1995 Mar;6(3):337-45; Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13876-83

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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