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Codon, Initiator

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Definition: A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.     
See Also Peptide Chain Initiation, Translational; Protein Biosynthesis 		Other names Initiator Codon; Codon, Start; Start Codons; Initiator Codons; Initiation Codons; Initiation Codon; Codons, Start; Codons, Initiator; Codons, Initiation; Start Codon; Codon, Initiation

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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