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Leukocyte-Adhesion Deficiency Syndrome

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Definition: Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.  an immunol defic syndrome; DF: LEUKOCYTE ADHESION DEFIC SYNDROME    Other names Syndromes, Leukocyte-Adhesion Deficiency; Syndrome, Leukocyte-Adhesion Deficiency; Leukocyte-Adhesion Deficiency Syndromes; Leukocyte Adhesion Deficiency Syndrome; Deficiency Syndromes, Leukocyte-Adhesion; Deficiency Syndrome, Leukocyte Adhesion; Deficiency Syndrome, Leukocyte-Adhesion
 
SubstanceCAS Registry & nameCategoriesSource
Leukocyte adhesion deficiency type 1  0   *Leukocyte-Adhesion Deficiency Syndrome.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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