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Receptors, Corticotropin

More information in Books or onNLM PubMed
Definition: Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.  DF: RECEPT ACTH   
Examples Receptors, Melanocortin 		Other names Receptors, Adrenocorticotropic Hormone; Receptors, ACTH; Corticotropin Receptors; Adrenocorticotropic Hormone Receptors; ACTH Receptors; Receptor, Corticotropin; Receptor, Adrenocorticotropic Hormone; Receptor, ACTH; Hormone Receptors, Adrenocorticotropic; Hormone Receptor, Adrenocorticotropic; Corticotropin Receptor; Adrenocorticotropic Hormone Receptor; ACTH Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
melanocortin 5a receptor protein, zebrafish  0   *Receptors, Corticotropin *Zebrafish Proteins. J Neurochem 2002 Jul;82(1):6-18
melanocortin 5b receptor protein, zebrafish  0   *Receptors, Corticotropin *Zebrafish Proteins. J Neurochem 2002 Jul;82(1):6-18
HS014 cyclic peptide  0   *Peptides, Cyclic Neuropeptides Receptors, Corticotropin/antagonists & inhibitors. Eur J Pharmacol 1998 Oct 30;360(1);15-9
HS 024  0   *Peptides, Cyclic Receptors, Corticotropin/antagonists & inhibitors. Endocrinology 1998 Dec;139(12):5006-14
alpha-MSH (1-13)amide, (Nle(4),Phe(p-I)7)  0   alpha-MSH/*analogs & derivatives Receptors, Corticotropin/antagonists & inhibitors. Am J Physiol 1998 Apr;274(4 Pt 2):R931-8
SHU 9119  168482-23-3   *Melanocyte-Stimulating Hormones Receptors, Corticotropin/antagonists & inhibitors. Nature 1997 Jan 9;385(6612):165-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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