Definition: One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)
/biosyn /physiol permitted; DF: note short X ref
Other names LTD4; Leukotriene D 4; Leukotrienes D; Leukotriene D-4; Leukotriene D
