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Sermorelin

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Definition: The biologically active fragment of human growth hormone-releasing factor, consisting of GHRH(1-29)-amide. This N-terminal sequence is identical in several mammalian species, such as human, pig, and cattle. It is used to diagnose or treat patients with GROWTH HORMONE deficiency.      Other names Somatotropin-Releasing-Hormone(1-29)Amide; Growth Hormone-Releasing Factor(1-29)Amide; Sermorelin Serono Brand; hGHRH(1-29)NH2; Serono Serono Brand of Sermorelin Acetate; Serono Brand of Sermorelin; Sermorelin Acetate; Geref; GRF(1-29)NH2; GHRH(1-29)NH2; Allphar Serono Brand of Sermorelin AcetateDrugs* : GEREF
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GHRH(1-29)NH2, (PhAc-Ada)(0)-Tyr(1), Arg(2), Fpa(5,6), Ala(8), Har(9), Tyr(Me)(10), His(11), Orn(12,) Abu(15), His(20), Orn(21), Nle(27), Arg(28), Har(29)  0   Sermorelin/*analogs & derivatives Growth Hormone-Releasing Hormone/antagonists & inhibitors. Cancer Lett 2010 Jul 1;293(1):31-40
GHRH(1-29)NH2, PhAcTyr(1)-Arg(2)-P(H)e(4-CL)(6)-Ala(8)-Tyr(Me)(10)-His(11)-Abu(15)-His(20)-Nle(27)-Arg(28)-HLCr(29)  0   Sermorelin/*analogs & derivatives. Oncol Rep 2008 Nov;20(5):1289-94
MZ-J-7-138  0   Sermorelin/*analogs & derivatives. Prostate 2008 Dec 1;68(16):1763-72
MZ-J-7-118  0   *Sermorelin. Clin Cancer Res 2005 Jan 1;11(1):49-57
somatotropin releasing hormone (1-29)amide, N-acetyl-Tyr(1),Arg(2)  0   Sermorelin/*analogs & derivatives. Eur J Endocrinol 2004 Nov;151(5);561-6
GRF-1PEG500  0   Sermorelin/*analogs & derivatives. Growth Horm IGF Res 2004 Jun;14(3):226-34
MZ 5-156  0   Sermorelin/*analogs & derivatives Growth Hormone-Releasing Hormone/antagonists & inhibitors. Peptides 1997;18(3):431-8
MZ 4-243  0   Sermorelin/*analogs & derivatives Growth Hormone-Releasing Hormone/antagonists & inhibitors. Endocrinology 1995 Sep;136(9):3849-55
MZ 4-71  0   Sermorelin/*analogs & derivatives Growth Hormone-Releasing Hormone/antagonists & inhibitors. Endocrinology 1995 Sep;136(9):3849-55
MZ 3-149  142186-15-0   Sermorelin/*analogs & derivatives. Int J Pept Protein Res 1993 Mar;41(3):246-9
somatotropin-releasing hormone (1-29), alpha-hydroxy-Gly(14)-Ala(15)  0   Sermorelin/*analogs & derivatives. Pept Res 1992 Jul-Aug;5(4):183-9
somatotropin-releasing hormone (1-29) amide, Ala(15)  0   Sermorelin/*analogs & derivatives. Pept Res 1992 Jul-Aug;5(4):183-9
somatotropin releasing hormone (1-29) NH2, desNH2Tyr(1)-Ala(2,15)  0   Sermorelin/*analogs & derivatives. J Med Chem 1992 Oct 16;35(21):3934-41
somatotropin releasing hormone(1-29)NH2, desNH2Tyr(1)-Ala(15)  0   *Peptide Fragments Sermorelin/*analogs & derivatives. Horm Metab Res 1991 Nov;23(11):530-4
somatotropin releasing hormone (1-29)NH2, Leu(27)-Ala(2)  0   *Peptide Fragments Sermorelin/*analogs & derivatives. Pept Res 1991 Mar-Apr;4(2):72-8
somatotropin releasing hormone (1-29) amide, 27-Leu  123041-18-9   Sermorelin/*analogs & derivatives. Drug Metab Dispos 1989;17(4):393
somatotropin releasing hormone (1-29)amide, N-acetyl-Tyr(1),Ala(2)  93942-88-2   Sermorelin/*analogs & derivatives. Peptides 1989;10(1):1
somatotropin releasing hormone (1-29)amide, N-acetyl-tyrosyl(1)-arginyl(2)  93942-91-7   Sermorelin/*analogs & derivatives. Endocrinology 1989;124(3):1154
DBO 29  109138-70-7   Sermorelin/*analogs & derivatives. Life Sci 1987;40(25):2437
somatotropin (1-29)amide, Nle(27)  91869-58-8   Sermorelin/*analogs & derivatives. Clin Pharmacol Ther 1986;40(6):627
somatotropin releasing hormone (1-29)-amide, N-Ac-Tyr(1)-Phe(2)  93965-89-0   Sermorelin/*analogs & derivatives.
Pharma Action Hormone Antagonists 		Endocrinology 1985;116(6):2643
somatotropin-releasing hormone (1-29)amide, Ala(2)  0   Sermorelin/*analogs & derivatives. Clin Endocrinol (Oxf) 1984;21(3):321

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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