encyclopedia of medical concepts
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Fenretinide
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Definition
: A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Pharmacological Action
Anticarcinogenic Agents
;
Antineoplastic Agents
Other names
4-
HPR; MCNR1967; MCN R 1967; Fenretinide, 13 cis Isomer; 4 Hydroxyphenylretinamide; 13-
cis-
Isomer Fenretinide; N-
(4-
Hydroxyphenyl)retinamide; N-
(4-
Hydroxyphenyl)-
trans-
Retinamide; MCN-
R-
1967; Fenretinimide; Fenretinide, 13-
cis-
Isomer; 4-
Hydroxyphenylretinamide
Substance
CAS Registry & name
Categories
Source
Drugs
*
4-
oxofenretinide
0
Fenretinide/*analogs & derivatives.
Clin Cancer Res 2004 Sep 15;10(18 Pt 1):6265-75
5-
hydroxyphenylbutanoateretinamide
0
Fenretinide/*analogs & derivatives.
Int J Cancer 2004 Mar10;109(1):58-64
N-
((4-
hydroxyphenyl)retinamide)-
O-
glucuronide
0
*Glucuronates
Fenretinide/*analogs & derivatives.
Anticancer Res 1993 Sep-Oct;13(5A):1431-6