Definition: The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors VIIIa and Va. A deficiency in protein S; (PROTEIN S DEFICIENCY); can lead to recurrent venous and arterial thrombosis.
a blood protein; an anticoagulant
Pharmacological ActionAnticoagulants
Other names Cofactor Protein S; Vitamin K-Dependent Protein S; Vitamin K Dependent Protein S; Protein S, Vitamin K Dependent; Protein S, Cofactor; Protein S, Vitamin K-Dependent