encyclopedia of medical concepts
ψ
ψ
Ribonuclease H
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Definition
: A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms as well as RETROVIRUSES.
Examples
Ribonuclease H, Human Immunodeficiency Virus
Other names
Ribonuclease H, Calf Thymus; Endoribonuclease H; RNase H; RNAase H
Substance
CAS Registry & name
Categories
Source
Drugs
*
NSC 727447
0
*Thiophenes
Ribonuclease H/antagonists & inhibitors.
ACS Chem Biol 2008 Oct 17;3(10):635-44
NSC 727448
0
*Furans
*Thiophenes
Ribonuclease H/antagonists & inhibitors.
ACS Chem Biol 2008 Oct 17;3(10):635-44
manicol
0
*Benzocycloheptenes
Ribonuclease H/antagonists & inhibitors
HIV Reverse Transcriptase/antagonists & inhibitors.
Nucleic Acids Res 2005;33(4):1249-56
beta-
thujaplicinol
0
Tropolone/*analogs & derivatives
Ribonuclease H/antagonists & inhibitors
HIV Reverse Transcriptase/antagonists & inhibitors.
Nucleic Acids Res 2005;33(4):1249-56
4-
(5-
(benzoylamino)thien-
2-
yl)-
2,4-
dioxobutanoic acid
0
*Butyric Acids
*Thiophenes
Ribonuclease H/antagonists & inhibitors.
J Biol Chem 2003 Jan 31;278(5):2777-80
PD 126338
0
*Hydrazones
*Carboxylic Acids
Ribonuclease H/antagonists & inhibitors.
Biochemistry 1999 Oct 5;38(40):13070-6
DNA polymerase, Thermus thermophilus
EC 2.7.7.-
*DNA-Directed DNA Polymerase
Exodeoxyribonucleases
Ribonuclease H.
Biochemistry 1995 Apr 18;34(15):4994-5002
ribonuclease HII
EC 3.1.26.-
*Ribonuclease H
Escherichia coli Proteins.
J Bacteriol 1995 Jan;177(1):264-7
ribonuclease HI
EC 3.1.26.4
*Ribonuclease H
Saccharomyces cerevisiae Proteins
Escherichia coli Proteins.
J Biol Chem 1993 Jan 5;268(1):88-92
illimaquinone
71678-03-0 2,5-
Cyclohexadiene-
1,4-
dione, 3-
((decahydro-
1,2,4a-
trimethyl-
5-
methylene-
1-
naphthalenyl)methyl)-
2-
hydroxy-
5-
methoxy-
, (1R-
(1alpha,2beta,4abeta,8aalpha))
*Quinones
Ribonuclease H/antagonists & inhibitors.
Antimicrob Agents Chemother 1990;34(10):2009
primase-
reverse transcriptase complex
0
*Multienzyme Complexes
*RNA-Directed DNA Polymerase
*Ribonuclease H
*DNA Primase.
Eur J Biochem 1991;195(1):157