Definition: Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see LYMPHOCYTE CULTURE TEST, MIXED). They are encoded by mouse mammary tumor viruses that have integrated into the germ line as DNA proviruses (MINOR LYMPHOCYTE STIMULATORY LOCI).
DF: note short X ref
Other names Mls Determinants; Mls Antigens; Minor Lymphocyte Stimulatory Determinants; Lymphocyte-Activating Determinants; Lymphocyte Stimulatory Antigens, Minor; Antigens, Minor Lymphocyte Stimulatory; Minor Lymphocyte Stimulating Determinants; Minor Lymphocyte Stimulating Antigens; Lymphocyte-Stimulating Determinants, Minor; Lymphocyte-Stimulating Antigens, Minor; Lymphocyte Activating Determinants; Determinants, Minor Lymphocyte-Stimulating; Determinants, Mls; Determinants, Lymphocyte-Activating; Antigens, Mls; Antigens, Minor Lymphocyte-Stimulating; Minor Lymphocyte-Stimulating Determinants; Minor Lymphocyte-Stimulating Antigens
