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Receptors, Antigen, T-Cell, gamma-delta

More information in Books or onNLM PubMed
Definition: T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3).  do not confuse with CD3 gamma & delta chains (index under ANTIGENS, CD3); DF: TCR G D   
See Also Gene Rearrangement, delta-Chain T-Cell Antigen Rec; Gene Rearrangement, gamma-Chain T-Cell Antigen Rec; Genes, T-Cell Receptor delta; Genes, T-Cell Receptor gamma
Other names TcR gamma-delta; T-Cell Receptors, gamma-delta; T-Cell Receptors gamma-Chain; T-Cell Receptors delta-Chain; Antigen Receptors, T-Cell, gamma-delta; gamma-delta T-Cell Receptors; gamma-delta T-Cell Receptor; gamma-Chain, T-Cell Receptors; gamma-delta, TcR; gamma-Chain, T-Cell Receptor; delta-Chain, T-Cell Receptors; delta-Chain, T-Cell Receptor; T Cell Receptors gamma Chain; T Cell Receptors delta Chain; T Cell Receptor, gamma delta; T Cell Receptor gamma Chain; T Cell Receptor delta Chain; T-Cell Receptor, gamma-delta; T-Cell Receptor gamma-Chain; T-Cell Receptor delta-Chain
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TCRVgamma9 protein, human  0   *Receptors, Antigen, T-Cell, gamma-delta. Blood 2009 May 14;113(20):4875-84
T-cell receptor Vdelta2, human  0   *Receptors, Antigen, T-Cell, gamma-delta. Cancer Immunol Immunother 2007 Aug;56(8):1285-97
T-cell receptor Vgamma9, human  0   *Receptors, Antigen, T-Cell, gamma-delta. Cancer Immunol Immunother 2007 Aug;56(8):1285-97
T-cell receptor V(gamma)3  0   *Receptors, Antigen, T-Cell, gamma-delta. Scand J Immunol 1992 Dec;36(6):833-41

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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