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Thymopentin

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Definition: Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. It is an immunomodulator which has been studied for possible use in the treatment of rheumatoid arthritis, AIDS, and other primary immunodeficiencies.     
Pharmacological Action Adjuvants, Immunologic 		Other names Thymopoietin Pentapeptide; TP-5; Pentapeptide, Thymopoietin; Timunox
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
beta-mercaptopropionyl-arginyl--lysyl-aspartyl-valyl-prolyl-cysteine amide  0   *Recombinant Proteins Thymopentin/*analogs & derivatives. Pol J Pharmacol 1996 Jan-Feb;48(1):31-8
CTP-2 peptide  0   Thymopentin/*analogs & derivatives. Pol J Pharmacol 1996 Jan-Feb;48(1);31-8
CTP-1 peptide  0   Thymopentin/*analogs & derivatives. Pol J Pharmacol 1996 Jan-Feb;48(1):31-8
IRI 514  0   *Oligopeptides Thymopentin/*analogs & derivatives. Physiol Behav 1996 Aug;60(2):397-401
thymopoietin pentapeptide-stilbene isothiocyanate  107878-40-0   *Thymopentin 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid/*analogs & derivatives. Int J Pept Protein Res 1987;29(2):177
thymopoietin pentapeptide-fluorescein isothiocyanate  107865-24-7   *Thymopentin Fluorescein-5-isothiocyanate/*analogs & derivatives. Int J Pept Protein Res 1987;29(2):177

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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