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Ganciclovir

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Definition: An ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.  do not confuse DHPG, a common abbrev for ganciclovir with DHPG for both 3,4-dihydroxyphenylglycol & 3,4-dihydroxyphenylethylene glycol   
Pharmacological Action Antiviral Agents 		Other names RS-21592; Gancyclovir; Ganciclovir, Monosodium Salt; Ganciclovir Sodium; Cytovene; BW-759; BIOLF-62Drugs* : GANCICLOVIR SODIUM; CYTOVENE; GANCICLOVIR; ZIRGAN; VITRASERT
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9-(3-fluoro-1-hydroxy-2-propoxy)methylguanine  0   Ganciclovir/*analogs & derivatives. Methods 2002 Jul;27(3):234-41
1-O-hexadecylpropanediol-3-phospho-penciclovir  0   Ganciclovir/*analogs & derivatives. Antivir Chem Chemother 2001 Jan;12(1):61-70
1-O-hexadecyl-propanediol-3-phospho-ganciclovir  0   Ganciclovir/*analogs & derivatives. Invest Ophthalmol Vis Sci 2000 May;41(6):1523-32
RS 79070-004  0   Ganciclovir/*analogs & derivatives. J Pharm Biomed Anal 1999 Nov;21(3):647-56
valganciclovir  0   Ganciclovir/*analogs & derivatives.
Pharma Action Antiviral Agents 		J Clin Pharmacol 1999 Aug;39(8):800-VALCYTE; VALGANCICLOVIR HYDROCHLORIDE
ganciclovir elaidate  0   Ganciclovir/*analogs & derivatives. Gen Ther 1998 Mar;5(3):419-26
9-((3-fluoro-1-hydroxy-2-propoxy)methyl)guanine  0   Ganciclovir/*analogs & derivatives Fluorine Radioisotopes. Nucl Med Biol 1996 Aug;23(6):787-92
ganciclovir cyclic phosphonate  0   *Cyclic P-Oxides *Phosphonic Acids Ganciclovir/*analogs & derivatives. Antimicrob Agents Chemother 1996 Aug;40(8):1964-6
6-deoxyganciclovir dipivalate ester  0   Ganciclovir/*analogs & derivatives. Drug Metab Dispos 1995 Nov;23(11):1242-7
ganciclovir triphosphate  0   Ganciclovir/*analogs & derivatives DNA-Directed DNA Polymerase/antagonists & inhibitors. Biochemistry 1995 Feb 28;34(8):2504-10
(3-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-4-hydroxybutyl)phosphonic acid  151006-30-3   Ganciclovir/*analogs & derivatives. J Med Chem 1994 Apr 29;37(9):1371-7
SR 3727A  150943-49-0   *Phosphonic Acids Ganciclovir/*analogs & derivatives. Antiviral Res 1993 Sep;22(1):77-89
ganciclovir kinase  EC 2.7.1.-   *Phosphotransferases (Alcohol Group Acceptor) Ganciclovir. Nature 1992 Jul 9;358(6382):160-2
3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-6-methyl-9-oxo-5H-imidazol(1,2-a)purine  134287-58-4   Ganciclovir/*analogs & derivatives. J Med Chem 1991;34(8):2380
9-(1-hydroxy-4-phosphinyl-2-butoxymethyl)guanine  104880-60-6   Ganciclovir/*analogs & derivatives. Antiviral Res 1986;6(5):299
9-((2,3-dihydroxy-1-propoxy)methyl)guanine  96429-66-2   Ganciclovir/*analogs & derivatives.
Pharma Action Antiviral Agents 		J Med Chem 1985;28(7):926

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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