Definition: Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
do not confuse with GLOMERULONEPHRITIS, MEMBRANOUS; do not make diagnoses: use the term used by the author
Other names Mesangiocapillary Glomerulonephritis; Membranoproliferative Glomerulonephritis; MPGN; Glomerulonephritis, Mesangiocapillary; Mesangiocapillary Glomerulonephritides; Membranoproliferative Glomerulonephritis, Subendot; Membranoproliferative Glomerulonephritides; Hypocomplementemic Glomerulonephritis; Hypocomplementemic Glomerulonephritides; Glomerulonephritides, Mesangiocapillary; Glomerulonephritides, Membranoproliferative; Glomerulonephritides, Hypocomplementemic; Subendothelial Membranoproliferative Glomeruloneph; Mesangiocapillary Glomerulonephritis, Type II; Mesangiocapillary Glomerulonephritis, Type I; Membranoproliferative Glomerulonephritis, Type III; Membranoproliferative Glomerulonephritis, Type II; Membranoproliferative Glomerulonephritis, Type I; Glomerulonephritis, Hypocomplementemic; Dense Deposit Disease
