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Fibrinogens, Abnormal

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Definition: Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing.  "have a functional defect as the result of one or more amino acid substitutions in the amino acid seq of normal fibrinogen"; DF: FIBRINOGENS ABNORM    Other names Abnormal Fibrinogens
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
fibrinogen Caracas VIII  0   *Fibrinogens, Abnormal. Thromb Haemost 2011 Apr;105(4):627-34
fibrinogen Fremantle  0   *Fibrinogens, Abnormal. Thromb Haemost 2010 Dec;104(6):1274-6
fibrinogen Znojmo  0   *Fibrinogens, Abnormal. J Thromb Thrombolysis. 2010 Oct;30(3):311-8
fibrinogen Rokycany  0   *Fibrinogens, Abnormal. J Thromb Thrombolysis. 2010 Oct;30(3):311-8
fibrinogen Zabrze  0   *Fibrinogens, Abnormal. Thromb Haemost 2010 Aug 2;104(2):415-7
fibrinogen Matsumoto VII  0   *Fibrinogens, Abnormal. Thromb Haemost 2010 Aug 2;104(2):213-23
fibrinogen Mannheim V  0   *Fibrinogens, Abnormal. Thromb Haemost. 2009 Jul;102(1):29-34
fibrinogen Frankfurt III, human  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 2009 Jul;20(5):366-70
fibrinogen Hershey IV  0   *Fibrinogens, Abnormal. Thomb Haemost 2008 Jun;99(6):1008-12
fibrinogen gamma'  0   *Fibrinogens, Abnormal. J Biol Chem 1975 Sep 25;250(18):7210-8
fibrinogen Novy Jicin  0   *Fibrinogens, Abnormal. Thromb Res 2007;121(1):75-84
fibrinogen Praha II  0   *Fibrinogens, Abnormal. Thromb Res 2007;121(1):75-84
fibrinogen Tolaga Bay  0   *Fibrinogens, Abnormal. Thromb Haemost. 2007 Nov;98(5):1136-8
fibrinogen Columbus  0   *Fibrinogens, Abnormal. Haematologica 2007 Aug;92(8):1151-2
fibrinogen Darlinghurst  0   *Fibrinogens, Abnormal. Thromb Haemost 2006 Nov;96(5):685-7
fibrinogen Guarenas  0   *Fibrinogens, Abnormal. Thromb Res 2006;118(5):637-50
fibrinogen Freiburg II  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 2006 Jan;17(1):63-7
fibrinogen Wilmington  0   *Fibrinogens, Abnormal. Thromb Haemost 2006 Jul;96(1):88-9
fibrinogen Mumbai  0   *Fibrinogens, Abnormal. Haematologica 2006 May;91(5):628-33
fibrinogen Caracas VI  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 2004 Oct;15(7):559-67
fibrinogen Caracas I  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 2004 Jun;15(4);285-93
fibrinogen Tottori II  0   *Fibrinogens, Abnormal. J Thromb Haemost 2003 Nov;1(11):2356-9
fibrinogen Otsu I, human  0   *Fibrinogens, Abnormal. Thromb Haemost 2003 Oct;90(4):757-8
fibrinogen Poissy II  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 2003 Apr;14(3):293-8
fibrinogen Perth  0   *Fibrinogens, Abnormal. J Thromb Haemost 2003 Jun;1(6);1245-50
fibrinogen Fukushima  0   *Fibrinogens, Abnormal. Clin Chim Acta 2002 Nov;325(1-2):151-6
fibrinogen Matsumoto II  0   *Fibrinogens, Abnormal. Thromb Res 2002 Aug 15;107(3-4):157-62
fibrinogen Merivale  0   *Fibrinogens, Abnormal Afibrinogenemia. Biochim Biophys Acta 2003 Feb 21;1645(2):146-51
fibrinogen San Giovanni Rotondo  0   *Fibrinogens, Abnormal. Thromb Haemost 2001 Dec;86(6):1483-8
fibrinogen Saint-Germain I  0   *Fibrinogens, Abnormal Coagulation Protein Disorders. Thromb Res 2001 Aug 1;103(3):201-7
fibrinogen Tahiti  0   *Fibrinogens, Abnormal Coagulation Protein Disorders. Thromb Res 2001 Aug 1;103(3):201-7
fibrinogen Poissy III  0   *Fibrinogens, Abnormal Coagulation Protein Disorders. Thromb Res 2001 Aug 1;103(3):201-7
fibrinogen Longmont  0   *Fibrinogens, Abnormal. Blood 2001 Aug 1;98(3):661-6
fibrinogen Matsumoto V  0   *Fibrinogens, Abnormal. Thromb Haemost 2001 Jan;85(1):108-13
fibrinogen Nieuwegein  0   *Fibrinogens, Abnormal. Blood 2001 Feb 15;97(4):973-80
fibrinogen Hakata  0   *Fibrinogens, Abnormal. Thromb Haemost 2000 Jul;84(1):49-53
fibrinogen Osaka VI  0   *Fibrinogens, Abnormal. Blood. 2000 Dec 1;96(12):3779-85
fibrinogen Caracas V  0   *Fibrinogens, Abnormal. Thromb Haemost 2000 Aug;84(2):263-70
fibrinogen Ales  0   *Fibrinogens, Abnormal. Blood 2000 Nov 15;96(10):3473-9
fibrinogen Vlissingen-Frankfurt IV  0   *Fibrinogens, Abnormal. J Biol Chem 2000 Jun 9;275(23):17778-85
fibrinogen Banks peninsula  0   *Fibrinogens, Abnormal. Haemostasis 1999;29(4):225-8
fibrinogen Milano XIII  0   *Fibrinogens, Abnormal. Thromb Res 1999 Dec 1;96(5):399-405
fibrinogen Matsumoto I  0   *Fibrinogens, Abnormal. Thromb Haemost 1996 Jun;75(6):887-91
fibrinogen Milano III  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 1996 Apr;7(3):331-5
fibrinogen Claro  0   *Fibrinogens, Abnormal. Thromb Res 1996 Jan 1;81(1):145-50
fibrinogen Canterbury  0   *Fibrinogens, Abnormal. J Clin Invest 1995 Dec;96(6):2854-8
fibrinogen Milano VII  0   *Fibrinogens, Abnormal. Blood 1994 Sep 15;84(6):1874-80
fibrinogen New Britain  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 1994 Apr;5(2):233-8
fibrinogen Bicetre II  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 1993 Oct;4(5):679-87
fibrinogen Mitaka II  0   *Fibrinogens, Abnormal. Blood 1993 Dec 15;82(12):3658-63
fibrinogen Bremen  0   *Fibrinogens, Abnormal. Thromb Haemost 1993 Sep 1;70(3):397-403
fibrinogen Bern I  152618-35-4 Fibrinogen Bern I  *Fibrinogens, Abnormal. Blood 1993 Oct 1;82(7):2104-8
fibrinogen Osaka IV  0   *Fibrinogens, Abnormal. Surg Today 1993;23(1):45-50
fibrinogen Marburg  0   *Fibrinogens, Abnormal. Blood 1992 Oct 15;80(8):1972-9
fibrinogen Milano IV  0   *Fibrinogens, Abnormal. Haemostasis 1992;22(1):7-11
fibrinogen IJmuiden  0   *Fibrinogens, Abnormal. Proc Natl Acad Sci U S A 1992 Apr 15;89(8):3478-82
fibrinogen Oviedo I  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 1990 Oct 1(4-5):571-5
fibrinogen Stony Brook II  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 1990 Oct;1(4-5):567-70
fibrinogen Lima  0   *Fibrinogens, Abnormal. Blood Coagul Fibrinolysis 1990 Oct;1(4-5):561-5
fibrinogen Osaka V  0   *Fibrinogens, Abnormal. J Biol Chem 1992 Feb 5;267(4):2753-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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