encyclopedia of medical concepts
ψ 
ψ 

2-Aminoadipic Acid

More information in Books or onNLM PubMed
Definition: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).     
Pharmacological Action Excitatory Amino Acid Antagonists 		Other names alpha-Aminoadipic Acid; alpha Aminoadipic Acid; Aminoadipic Acid, 2; Acid, alpha-Aminoadipic; Acid, 2-Aminohexanedioic; Acid, 2-Aminoadipic; Acid, 2 Aminoadipic; 2 Aminohexanedioic Acid; 2-Aminohexanedioic Acid; 2 Aminoadipic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-phosphopyridoxyl-alpha-aminoadipate  0   Pyridoxal Phosphate/*analogs & derivatives 2-Aminoadipic Acid/*analogs & derivatives. Proteins 2009 May 1;75(2):348-59
N(alpha)-benzyloxycarbonyl-aminoadipic acid  0   2-Aminoadipic Acid/*analogs & derivatives. J Biosci Bioeng 2007 Nov;104(5):398-402
N(alpha)-benzyloxycarbonylaminoadipic acid delta-semialdehyde  0   2-Aminoadipic Acid/*analogs & derivatives. J Biosci Bioeng 2005 Sep;100(3):288-91
N-(1-((2,4-diamino-6-pteridinyl)methyl)-3,4-dihydro -2H-1,4-benzothiazine-7-carbonyl)-L-2-aminoadipic acid  0   Methotrexate/*analogs & derivatives 2-Aminoadipic Acid/*analogs & derivatives. Immunopharmacology 1996 Oct;35(1):41-6
allysine ethylene acetal  0   *Acetals 2-Aminoadipic Acid/*analogs & derivatives. Bioorg Med Chem 1995 Sep;3(9):1237-40
N-(N-(4-(N-((3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl)-2-propynylamino)benzoyl)-gamma-glutamyl)-2-aminoadipic acid  0   Folic Acid/*analogs & derivatives 2-Aminoadipic Acid/*analogs & derivatives Thymidylate Synthase/antagonists & inhibitors. J Med Chem 1994 Sep 30;37(20):3294-302
2-amino-4,5-methanoadipate  127515-30-4   2-Aminoadipic Acid/*analogs & derivatives. Farmaco 1991 Nov;46(11):1243-1264
phthalyl-allysine-4-nitrobenzyl ester  121145-63-9   *Benzyl Compounds *Phthalic Acids 2-Aminoadipic Acid/*analogs & derivatives. Connect Tissue Res 1989;18(4):255
hydroxyallysine  30382-02-6   2-Aminoadipic Acid/*analogs & derivatives. Annu Rev Biochem 1984;53:717
alpha-amino-gamma,delta-dihydroxyadipic acid  66660-16-0 Hexaric acid, 2-amino-2,3-dideoxy  2-Aminoadipic Acid/*analogs & derivatives. BBA 540:93;1978
allysine aldol  53129-41-2 Undecanedioic acid, 2,10-diamino-5-formyl-6-hydroxy  2-Aminoadipic Acid/*analogs & derivatives. Biochim Biophys Acta 295(1):301;25Jan73
allysine  1962-83-0 alpha-aminoadipic semialdehyde  2-Aminoadipic Acid/*analogs & derivatives. Jpn J Exp Med 45(4):313;1975; Proc Natl Acad Sci USA 75(8):3708;1978

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy