encyclopedia of medical concepts
ψ 
ψ 
ψ 

Tubercidin

More information in Books or onNLM PubMed
Definition: An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.  an antineoplastic antimetabolite   
Pharmacological Action Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic 		Other names 7-Deazaadenosine; 7 Deazaadenosine; Deazaadenosine; 4-Amino-7 beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)py
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,N6-etheno-2'-deoxytubercidin hemihydrat  0   Tubercidin/*analogs & derivatives. Acta Crystallogr C. 2011 Mar;67(Pt 3):o111-4
7-deaza-2'-C-methyl-7-fluoroadenosine  0   Tubercidin/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2009 Aug;28(8):772-5
7-deaza-7-ethynyl-2'-C-methyladenosine  0   Tubercidin/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2008;(52):643-4
7-deaza-7-ethynyl-2'-deoxy-2'-fluoro-2'-C-methyladenosine  0   Tubercidin/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2008;(52):643-4
JK 273  0   *Aniline Compounds Tubercidin/*analogs & derivatives. Bioorg Med Chem 2009 Feb 1;17(3):977-80
2-amino-7-chloro-2'-deoxytubercidin  0   Tubercidin/*analogs & derivatives. Acta Crystallogr C 2006 Oct;62(Pt 10):o593-5
7-deaza-2'-C-methyladenosine  0   Tubercidin/*analogs & derivatives. J Infect Dis 2007 Mar 1;195(5):665-74
5-iodo-5'-deoxytubercidin  0   Tubercidin/*analogs & derivatives Adenosine Kinase/antagonists & inhibitors. J Med Chem 2006 Nov 16;49(23):6726-31
2'-naphthylmethyl-2'-deoxytubercidine  0   Tubercidin/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1289-91
carboline-benzoquinolizidine alkolid deoxytubulosine  0   *Quinolizines *Tubercidin Thymidylate Synthase/antagonists & inhibitors. J Biochem Mol Toxicol 1998;12(3):167-73
7-deazanebularin  16754-83-9   Tubercidin/*analogs & derivatives.
7-iodotubercidin  0   Tubercidin/*analogs & derivatives. Biochem Pharmacol 1995 May 17;49(10):1501-12
3-deaza-2'-deoxyadenosine  78582-17-9   Tubercidin/*analogs & derivatives. Nucleic Acids Res 1990;18(16):4771
5-(methoxycarbonyl)tubercidin  18440-68-1   Tubercidin/*analogs & derivatives. J Nat Prod 1989;52(6):1353
2-chloro-2'-deoxy-3,7-dideazaadenosine  114915-05-8   Tubercidin/*analogs & derivatives. J Med Chem 2989;32(7):1463
ara-tubercidin 5'-triphosphate  78153-66-9   *Arabinonucleotides Tubercidin/*analogs & derivatives. Antiviral Res 1987;8(2):97
ara-tubercidin  64526-34-7   *Arabinonucleosides Tubercidin/*analogs & derivatives. Antiviral Res 1987;8(2):97
2'-deoxy-3,7-dideazaadenosine  114915-06-9   Tubercidin/*analogs & derivatives. Nucleic Acids Res 1987;15(17):7208
2'-deoxytubercidin  60129-59-1   Tubercidin/*analogs & derivatives. Biochemistry 1987;26(8):2232
5'-methylthio-5'-deoxy-9-deazaadenosine  106175-18-2   Tubercidin/*analogs & derivatives Purine-Nucleoside Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1987;36(13):2063
5'-chloro-5'-deoxy-9-deazaadenosine  67377-77-9   Tubercidin/*analogs & derivatives Purine-Nucleoside Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1987;36(13):2063
xylotubercidin  64526-29-0   Tubercidin/*analogs & derivatives. Antimicrob Agents Chemother 1986;30(5):719
1-deazaadenosine  14432-09-8 3H-Imidazo(4,5-b)pyridin-7-amine, 3-beta-D-ribofuranosyl  *Tubercidin Isomerism. Pharmacol Res Commun 1985;17(12):1087
1,3-dideazaadenosine  20649-47-2   Tubercidin/*analogs & derivatives. Pharmacol Res Commun 1985;17(12):1087
3-(4-amino-1H-pyrrolo(2,3-d)pyrimidin-1-yl)-5-(hydroxymethyl)-1,2-cyclopentanediol  88767-13-9   Tubercidin/*analogs & derivatives. J Med Chem 1984;27(4):534
5'-deoxy-5-iodotubercidin  0   Tubercidin/*analogs & derivatives Adenosine Kinase/antagonists & inhibitors. Biochem Pharmacol 1984;33(3):347
9-deazaadenosine  77691-03-3 D-Ribitol, 1-C-(4-amino-5H-pyrrolo(3,2-d)pyrimidin-7-yl)-1,4-anhydro-, (S)  Tubercidin/*analogs & derivatives. Biochem Pharmacol 1983;32(7):1211
1-deazatubercidin  83683-90-3 1H-Pyrrolo(2,3-b)pyridin-4-amine, 1-beta-D-ribofuranosyl  Tubercidin/*analogs & derivatives. J Med Chem 1982;25(10):1258
tubercidin 5'-phosphate  16719-46-3   *Adenine Nucleotides Tubercidin/*analogs & derivatives. Biochemistry 1982;21(5):886
tubercidin-5'-diphosphate  21080-53-5   *Adenine Nucleotides Tubercidin/*analogs & derivatives. Biochemistry 1982;21(5):886
5-iodotubercidin  24386-93-4   Tubercidin/*analogs & derivatives Adenosine Kinase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Biochem J 1981;200(2):399
carbocyclic 3-deazaadenosine  81601-33-4 1,2-Cyclopentanediol, 3-(4-amino-1H-imidazo(4,5-c)pyridin-1-yl)-5-(hydroxymethyl)-, (1alpha,2alpha,3beta,5beta)-(+-)  Tubercidin/*analogs & derivatives. J Med Chem 1982;25(6):626
tubercidin 5'-diphosphate-5'-1,2-dipalmitin  78679-20-6 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 7-(5-O-(1,3-dihydroxy-6-((1-oxohexadecyl)oxy)-9-oxo-2,4,8-trioxa-1,3-diphosphatetracos-1-yl)-beta-D-arabinofuranosyl)-, P,P'-dioxide, (R)  Tubercidin/*analogs & derivatives. Cancer Res 1981;41(7):2707
5-chlorotubercidin  24386-95-6   Tubercidin/*analogs & derivatives. Nucleic Acids Res 1980;8(24):6213
5'-methylthiotubercidin  61893-98-9 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 7-(5-S-methyl-5-thio-beta-D-ribofuranosyl)  *Thionucleosides Tubercidin/*analogs & derivatives. Biochim Biophys Acta 1979;588(3):294; Biochim Biophys Acta 570(1):65;1979
3-deazaadenosine  6736-58-9   *Tubercidin Isomerism. Biochem Biophys Res Commun 84(1):102;1978; Proc Natl Acad Sci USA 75(12):6220;1978
2'-deoxytubercidin-5'-triphosphate  67460-15-5 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, 7-(2-deoxy-5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-erythro-pentofuranosyl)  Tubercidin/*analogs & derivatives. Adv Enz Regul 1978;17:164; Biochemistry 17(12):2350;1978
5'-deoxy-5'-(isobutylthio)-3-deazaadenosine  67377-76-8 1H-Imidazo(4,5-c)pyridin-4-amine, 1-(5-S-(2-methylpropyl)-5-thio-beta-D-ribofuranosyl)  Tubercidin/*analogs & derivatives. Biochem Biophys Res Commun 82(2):417;1978
tubercidin 5'-triphosphate  10058-66-9 5-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidin-4-amine  *Adenine Nucleotides Tubercidin/*analogs & derivatives. Biochem Biophys Res Commun 57(2):434;1974
tubercidin 3',5'-cyclic phosphate  16719-36-1 7-(3,5-O-phosphinico-beta-D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidin-4-amine  Tubercidin/*analogs & derivatives. Biochem Biophys Res Commun 55(3):843;1973
5-hydroxymethyltubercidin  49558-38-5 4-amino-7-beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-methanol  Tubercidin/*analogs & derivatives. J Med Chem 16(12):1405;1973
bromotubercidin  21193-80-6   Tubercidin/*analogs & derivatives. J Exp Med 134(4):955;1971

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy