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Trioxsalen
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Definition
: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
Pharmacological Action
Photosensitizing Agents
Other names
Trioxysalen; Trimethylpsoralen; NSC71047; NSC 71047; Trisoralen; Trioxisalenum; ICN Brand of Trioxsalen; 4,5',8-
Trimethylpsoralen; 2,5,9-
Trimethyl-
7H-
furo(3,2-
g)benzopyran-
7-
one; NSC-
71047
Drugs
*
:
TRISORALEN
Substance
CAS Registry & name
Categories
Source
Drugs
*
iodomercurio-
4',5'-
dihydrotrimethylpsoralen
0
*Organomercury Compounds
Trioxsalen/*analogs & derivatives.
Biochem Pharmacol 2005 Dec 5;70(12):1726-34
psoAG10 compound
0
*Oligonucleotides
Trioxsalen/*analogs & derivatives.
J Biol Chem 1995 Sep 22;270(38):22595-601
1,15-
bis(4'-
trioxsalen)-
2,6,10,14-
tetramethyl-
2,6,10,14-
tetrazapentadecane
84067-18-5 7H-
Furo(3,2-
g)(1)benzopyran-
7-
one, 4,4'-
(2,6,10,14-
tetramethyl-
2,6,10,14-
tetraazapentadecane-
1,15-
diyl)bis(2,5,9-
trimethyl)
Trioxsalen/*analogs & derivatives.
J Mol Biol 1982;159(1)
2-
pyridyldithioethylmethylamidodiethoxyethane methylaminomethyltrimethylpsoralen
83353-04-2 Propanamide, N-
methyl-
N-
(2-
(2-
(2-
(methyl((2,5,9-
trimethyl-
7-
oxo-
7H-
furo(3,2-
g)(1)benzopyran-
3-
yl)methyl)amino)ethoxy)ethoxy)ethyl)-
3-
(2-
pyridinyldithio)
Trioxsalen/*analogs & derivatives.
Proc Natl Acad Sci USA 1982;79(15):4594
4,8-
dimethyl-
5'-
carboxypsoralen
15912-90-0 5,9-
dimethyl-
7-
oxo-
7H-
furo(3,2-
g)(1)benzopyran-
2-
carboxylic acid
Trioxsalen/*analogs & derivatives.
Farmaco(Sci) 34(3):234;1979
aminomethyltrioxsalen
64358-50-5 7H-
furo(3,2-
g)(1)benzopyran-
7-
one, 3-
(aminomethyl)-
2,5,9-
trimethyl
Trioxsalen/*analogs & derivatives
Tritium.
Pharma Action
Cross-Linking Reagents
;
Photosensitizing Agents
;
Anti-HIV Agents
Biochemistry 1979;18(13):2905; Biochim Biophys Acta 563(2):343;1979; Eur J Biochem 95(1):203;1979; Nucleic Acids Res 1979;7(3):689; Proc Natl Acad Sci USA 76(2):755;1979
hydroxymethyltrioxsalen
62442-59-5 3-
(hydroxymethyl)-
2,5,9-
trimethyl-
7H-
furo(3,2-
g)(1)benzopyran-
7-
one
Trioxsalen/*analogs & derivatives.
Pharma Action
Cross-Linking Reagents
Proc Natl Acad Sci USA 75(4):1642;1978