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Tricarboxylic Acids

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Definition: Organic compounds that are acyclic and contain three acid groups. A member of this class is citric acid which is the first product formed by reaction of pyruvate and oxaloacetate. (From Lehninger, Principles of Biochemistry, 1982, p443)  /metab is probably TRICARBOXYLIC ACID CYCLE   
Examples Aconitic Acid; 1-Carboxyglutamic Acid; Citrates 		Other names Acids, Tricarboxylic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-acryloyloxyethyltrimellitic acid  0   *Acrylates *Tricarboxylic Acids. Dent Mater J 2009 Sep;28(5):558-64
homoisocitric acid  0   *Tricarboxylic Acids. Biochemistry 1975 Jun 17;14(12):2581-8
trimethyl cis,cis-1,3,5-tripropyl-1,3,5 cyclohexenetricarboxilic acid  0   *Cyclohexanes *Tricarboxylic Acids. Water Environ Res. 2006 Jan;78(1):69-75
pyridine-2,4,6-tricarboxylic acid  0   *Pyridines *Tricarboxylic Acids. Inorg Chem. 2004 Sep 6;43(18):5495-7
6,7-dideoxysqualestatin H5  0   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic. J Org Chem 2002 Jun 14;67(12):4200-8
1,3,5-trimethylcyclohexane-1,3,5-tricarboxylic acid  0   *Cyclohexanes *Tricarboxylic Acids. J Org Chem 2002 Mar 8;67(5):1630-6
sucrose tricarboxylic acid  0   *Tricarboxylic Acids Sucrose/*analogs & derivatives. Carbohydr Res 2000 Jun 16;326(3):176-84
1-aminocyclopentane-1,2,4-tricarboxylic acid  0   *Cyclopentanes *Tricarboxylic Acids. J Neurophysiol 2000 May;83(5):2519-25
zaragozic acid D3  0   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. J Antibiot (Tokyo) 1998 Apr;51(4):428-31
4-acryloxyethyltrimellitic acid  0   *Tricarboxylic Acids. Dent Mater J 1996 Dec;15(2):132-43
1-aminocyclopentane-1,3,4-tricarboxylic acid  0   *Cyclopentanes *Tricarboxylic Acids Stereoisomerism. J Med Chem 1997 Sep 12;40(19):3119-29
Oreganic acid  0   *Tricarboxylic Acids Transferases/antagonists & inhibitors. Biochem Biophys Res Commun 1997 Mar 17;232(2):478-81
tris(3,5-dibromosalicyl) tricarballylate  137656-90-7   *Salicylates *Tricarboxylic Acids. Artif Cells Blood Substit Immobil Biotechnol 1996 Nov;24(6):587-98
N-(3-(3-(1-piperidinyl-methyl)phenoxy)propyl)hydroxyacetamide 2-hydroxypropane-1,2,3-tricarboxylate bismuth (3+) complex  0   *Organometallic Compounds *Piperidines *Tricarboxylic Acids Bismuth. J Pharm Pharmacol 1996 Mar;48(3):297-301
4-methacryloxyethyltrimellitic acid  68183-31-3   *Methacrylates *Tricarboxylic Acids Resin Cements. Dent Mater 1995 May;11(3):191-5
TAN 1607A  0   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. Biochem Biophys Res Commun 1996 Feb 15;219(2):515-520
squalestatin 3  142505-92-8   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. Phytochemistry 1995 Mar;38(5):1137-41
squalestatin 2  142505-91-7   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. Phytochemistry 1995 Mar;38(5):1137-41
2,4,5-piperidinetricarboxylic acid  0   *Pipecolic Acids *Tricarboxylic Acids. Z Naturforsch (C) 1994 Nov-Dec;49(11-12):707-11
methylhomocitric acid  0   *Tricarboxylic Acids. Clin Chim Acta 1994 Oct 14;230(1):91-9
zaragozic acid D(2)  155179-15-0   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. J Nat Prod 1993 Nov;56(11):1923-9
zaragozic acid D  155179-14-9   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors. J Nat Prod 1993 Nov;56(11):1923-9
2-hexylindole-3-acetamide-N-benzenetricarboxylic acid  152842-64-3 1,2-Benzenedicarboxylic acid, 4-((3-(2-(dihexylamino)-2-oxoethyl)-2-(4-fluorophenyl)-1H-indol-1-yl)carbonyl)  *Indoleacetic Acids *Tricarboxylic Acids. J Pharmacol Exp Ther 1993 Oct;267(1):462-71
squalestatin 1  142561-96-4   *Tricarboxylic Acids *Bicyclo Compounds, Heterocyclic Farnesyl-Diphosphate Farnesyltransferase/antagonists & inhibitors.
Pharma Action Anticholesteremic Agents ; Antifungal Agents ; Enzyme Inhibitors 		J Biol Chem 1992 Jun 15;267(17):11705-8
4-Met adhesion promoting monomer  0   *Methacrylates *Tricarboxylic Acids Resin Cements. Shika Zairyo Kikai 1990 Nov;9(6):888-93
octylmethane-tri-(2-oxabutanoic acid)  142181-63-3   *Ethers *Tricarboxylic Acids. Arch Immunol Ther Exp (Warsz) 1991;39(1-2):165-8
trimesic acid  554-95-0   *Tricarboxylic Acids. Strahlenther Onkol 1991;167(6):366
1-fluorohomocitrate  131736-83-9   *Tricarboxylic Acids. Proc Natl Acad Sci USA 1990;87(17):6517
N-sulfo-2-aminotricarballylate  86883-55-8 1,2,3-Propanetricarboxylic acid, 2-(sulfoamino)  *Tricarboxylic Acids. Anal Biochem 1983;132(1):115
4-oxalmesaconic acid  85179-60-8   *Tricarboxylic Acids. J Biochem (Tokyo) 1983;93(2):567
homocitric acid  3562-74-1   *Tricarboxylic Acids. J Bacteriol 1980;144(3):869
tricarballylic acid  99-14-9   *Tricarboxylic Acids. Zentralbl Bakteriol (B) 1980;135(5):435
trimellitic acid  528-44-9 1,2,4-benzenetricarboxylic acid  *Tricarboxylic Acids. Clin Allergy 7:1;1977; Eur J Biochem 78(1):183;1977
caperatic acid  29227-64-3 2-hydroxy-1,2,3-heptadecanetricarboxylic acid monomethyl ester  *Tricarboxylic Acids. Arch Farmacol Toxicol 2(2):143;1976
carboxymuconolactone  13249-46-2 2-Furanacetic acid, 2-carboxy-2,5-dihydro-5-oxo  *Tricarboxylic Acids. Biochemistry 12(18):3537;1973
benzene 1,2,3-tricarboxylic acid  569-51-7   *Benzene Derivatives *Tricarboxylic Acids. Acta Biochem Polon 23(2-3):93;1976; Biochem Biophys Res Commun 52(3):981;1973; Biochim Biophys Acta 380(3):378;1975; Europ J Biochem 38(1):98;1973; Int J Biochem 9:317;1978; J Biol Chem 252(16):5661;1977
1,2,3-tricarboxy-1-cyclopentene  31602-26-3 1-Cyclopentene-1,2,3-tricarboxylic acid  *Tricarboxylic Acids. Arch Biochem Biophys 147(2):772;1971

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