encyclopedia of medical concepts
ψ
Teprotide
More information
in Books
or on
Definition
: A synthetic nonapeptide (Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) which is identical to the peptide from the venom of the snake, Bothrops jararaca. It inhibits kininase II and ANGIOTENSIN I and has been proposed as an antihypertensive agent.
Pharmacological Action
Angiotensin-Converting Enzyme Inhibitors
;
Antihypertensive Agents
Other names
Peptide 9a, Bradykinin-
Potentiating; Nonapeptide Converting Enzyme Inhibitor; Enzyme Inhibitor, Nonapeptide-
Converting; Bradykinin Potentiating Peptide 9a; SQ-
20881; Nonapeptide-
Converting Enzyme Inhibitor; Bradykinin-
Potentiating Peptide 9a; BPP-
9a
Substance
CAS Registry & name
Categories
Source
Drugs
*
GF 109
79873-93-1 L-
Proline, 3,4-
didehydro-
1-
(1-
(N-
(N2-
(1-
(N2-
(3,4-
didehydro-
1-
(N-
L-
alpha-
glutamyl-
L-
tryptophyl)-
L-
prolyl)-
L-
arginyl)-
L-
prolyl)-
L-
glutaminyl)-
L-
isoleucyl)-
L-
prolyl)
Teprotide/*analogs & derivatives.
Biochem Pharmacol 1981;30(13):1869
GF 94
80658-46-4 L-
Proline, 1-
(1-
(N-
(N2-
(1-
(N2-
(3,4-
didehydro-
1-
(N-
L-
alpha-
glutamyl-
L-
tryptophyl)-
L-
prolyl)-
L-
arginyl)-
L-
prolyl)-
L-
glutaminyl)-
L-
isoleucyl)-
L-
prolyl)
Teprotide/*analogs & derivatives.
Biochem Pharmacol 1981;30(13):1869
