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Taurocholic Acid

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Definition: The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.  /biosyn /physiol permitted   
Pharmacological Action Cholagogues and Choleretics; Detergents
Examples Taurodeoxycholic Acid; Taurolithocholic Acid 		Other names Taurocholate; Taurine Cholate; Cholyltaurine; Taurocholate, Sodium; Taurocholic Acid, Monosodium Salt; Taurocholic Acid, Monolithium Salt; Taurocholic Acid, (7 beta)-Isomer; Taurocholic Acid, (5 alpha)-Isomer; Taurocholate Sodium; Sodium Taurocholate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3alpha,6alpha,7alpha,12alpha-tetrahydroxy-cholanoyl taurine  0   Taurocholic Acid/*analogs & derivatives. Drug Metab Dispos. 2010 Oct;38(10):1723-30
TC002  0   *Glycosides Taurocholic Acid/*analogs & derivatives. Pharm Res 1998 Dec;15(12):1876-81
chlorambucil-taurocholate  0   Chlorambucil/*analogs & derivatives Taurocholic Acid/*analogs & derivatives Drug Carriers. Gastroenterology 1997 Oct;113(4):1295-305
4'-amino-7-benzamidotaurocholic acid  0   Taurocholic Acid/*analogs & derivatives. Arch Biochem Biophys 1994 Mar;309(2):329-40
(N-(7-(nitrobenz-2-oxa-1,3-diazol-4-yl))-7-amino-3alpha,12alpha-dihydroxycholan-24-oyl)-2-aminoethanesulfonate  124882-57-1   *Oxadiazoles Taurocholic Acid/*analogs & derivatives. Am J Physiol 1993 Feb;264(2 Pt 1):G220-30
tauropythocholoic acid  0   Taurocholic Acid/*analogs & derivatives. Yao Hsueh Hsueh Pao 1992;27(9):674-8
tauro 1-hydroxycholic acid  142608-64-8   Taurocholic Acid/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1992 Mar;40(3):701-4
hexadecyltributylammonium taurocholate  124536-25-0   *Quaternary Ammonium Compounds Taurocholic Acid/*analogs & derivatives. Biosens Bioelectron 1990;5(3):215
azidobenzamidotaurocholate  125378-99-6   *Azides Taurocholic Acid/*analogs & derivatives. Biochim Biophys Acta 1989;980(2):161
3,12-dihydroxy-7-oxocholanoyltaurine  67460-69-9   Taurocholic Acid/*analogs & derivatives. Am J Physiol 1984;246(2 pt 1):G166
3-hydroxy-7-oxocholanoyltaurine  75808-01-4 Ethanesulfonic acid, 2-(((3alpha,5beta)-3-hydroxy-7,24-dioxocholan-24-yl)amino)-, (SP-4-2)  Taurocholic Acid/*analogs & derivatives. Am J Physiol 1984;246(2 pt 1):G166
tauronorcholic acid  87700-06-9 Ethanesulfonic acid, 2-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-23-oxo-24-norcholan-23-yl)amino)  Taurocholic Acid/*analogs & derivatives. Biochem J 1983;214(3):923
taurocholate carrier protein, rat  0   *ATP-Binding Cassette Transporters Taurocholic Acid. J Biol Chem 1983;258(14):8896
tauroglycocholic acid  11006-55-6   Taurocholic Acid/*analogs & derivatives. J Appl Bacteriol 1983;54(1):127
tauromuricholic acid  25696-60-0   Taurocholic Acid/*analogs & derivatives. FEBS Lett 1983;151(1):19
23-seleno-25-homotaurocholic acid  75018-70-1   Taurocholic Acid/*analogs & derivatives Selenium Radioisotopes. J Nucl Med 1982;23(2):126
taurodehydrocholate  517-37-3   Taurocholic Acid/*analogs & derivatives. Am J Physiol 236(1):E10;1979
tauro-3,7-dihydroxy-12-ketocholanoic acid  67460-70-2 Ethanesulfonic acid, 2-(((3alpha,5beta,7alpha)-3,7-dihydroxy-12,24-dioxocholan-24-yl)amino)  Taurocholic Acid/*analogs & derivatives. Am J Physiol 234(6):E637;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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