encyclopedia of medical concepts
ψ 
ψ 

Streptonigrin

More information in Books or onNLM PubMed
Definition: Complex cytotoxic antibiotic obtained from Streptomyces flocculus or S. rufochronmogenus. It is used in advanced carcinoma and causes leukopenia.     
Pharmacological Action Antibiotics, Antineoplastic 		Other names Rufocromomycin; Bruneomycin; NSC45383; NSC 45383; Nigrin; NSC-45383; Brunemycin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
decarboxy-2'-(hydroxymethyl)-demethyllavendamycin  0   Streptonigrin/*analogs & derivatives. J Med Chem 2005 Dec 1;48(24):7733-49
7-(1-methyl-2-oxopropyl)streptonigrin  0   Streptonigrin/*analogs & derivatives. J Nat Prod 2002 May;65(5):721-4
retrostatin  0   *Streptonigrin. J Antibiot (Tokyo) 1983 Jul;36(7):761-9
2'-decarboxy-2'-aminostreptonigrin  143139-76-8   Streptonigrin/*analogs & derivatives. J Antibiot (Tokyo) 1992 Jun;45(6):1002-4
10'-desmethoxystreptonigrin  136803-89-9   Streptonigrin/*analogs & derivatives. J Antibiot (Tokyo) 1992 Apr;45(4):454-7
di-2',8'-O-di-5',5'-N,N-methylstreptonigrone  140458-71-5   Streptonigrin/*analogs & derivatives Streptomyces. J Antibiot (Tokyo) 1992 Feb;45(2):227-34
tri-1',5',5'-N,N,N-mono-8'-O-methylstreptonigrone  140458-70-4   Streptonigrin/*analogs & derivatives Streptomyces. J Antibiot (Tokyo) 1992 Feb;45(2):227-34
10'-O-demethylstreptonigrin  105933-56-0   Streptonigrin/*analogs & derivatives. J Antibiot (Tokyo) 1986;39(7):1013
streptonigrone  96684-38-7   Streptonigrin/*analogs & derivatives. J Antibiot 1985;38(4):516
lavendamycin  81645-09-2 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl  Streptonigrin/*analogs & derivatives. J Antibiot (Tokyo) 1982;35(3):259

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy