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Sincalide

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Definition: An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.  do not confuse with Sincaline (   
See Also Appetite Depressants; Gastrointestinal Agents 		Other names Cholecystokinin Octapeptide; CCK-8; SQ19844; SQ19,844; SQ 19844; SQ 19,844; Cholecystokinin Pancreozymin C Terminal Octapeptid; Syncalide; SQ-19844; SQ-19,844; OP-CCK; Kinevac; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; Cholecystokinin Pancreozymin C-Terminal Octapeptid; CCK-OP; Bracco Brand of SincalideDrugs* : KINEVAC
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
indium DTPA-Glu-G-CCK8  0   Pentetic Acid/*analogs & derivatives Sincalide/*analogs & derivatives. J Nucl Med 2004 Mar;45(3):485-94
cholecystokinin (26-33) sulfated amide  0   *Peptide Fragments Sincalide/*analogs & derivatives. Diabetes 2001 Nov;50(11):2505-13
cholecystokinin (26-32), rhodamine-Tyr-Gly-Nle(28,31) phenethyl ester  0   *Rhodamines Sincalide/*analogs & derivatives. Am J Physiol 1999 Mar;276(3 Pt 1):C539-C547
AR C15849KF  0   Sincalide/*analogs & derivatives. J Pharm Biomed Anal 1998 Aug;17(4-5):793-800
cholecystokinin (26-33), I-Tyr-Gly-(Nle(28,31),4-NO2-Phe(33))  118643-58-6   *Peptide Fragments Sincalide/*analogs & derivatives. Anal Biochem 1994 Aug 1;220(2):434-5
8-sulfocholecystokinin octapeptide  0   Sincalide/*analogs & derivatives Receptors, Cholecystokinin/agonists.
Pharma Action Nootropic Agents 		Peptides 1994;15(4):689-97
FPL 14294  154132-95-3 L-Phenylalaninamide, N-((4-(sulfooxy)phenyl)acetyl)-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-Nalpha-methyl  Sincalide/*analogs & derivatives. Pharmacol Biochem Behav 1994 Mar;47(3):701-8
SUT 8701  123577-73-1 L-Phenylalaninamide, N-((1,1-dimethylethoxy)carbonyl)-O-(dimethylphosphinyl)-L-tyrosyl-L-norleucylglycyl-L-tryptophyl-L-norleucyl-L-alpha-aspartyl  Sincalide/*analogs & derivatives. Jpn J Pharmacol 1993 Apr;61(4):341-9
JMV 332  130582-12-6 L-Phenylalaninamide, N2-acetyl-N6-(3-carboxy-1-oxopropyl)-L-lysylglycyl-L-tryptophyl-L-lysyl-L-alpha-aspartyl-, cyclic (1-4)-peptide  Sincalide/*analogs & derivatives. Peptides 1992 Nov-Dec;13(6):1227-32
desulfated sincalide  25679-24-7   Sincalide/*analogs & derivatives. Surgery 1993 Feb;113(2):155-62
JMV 320  130582-10-4   Sincalide/*analogs & derivatives. Ann Surg 1992 May;215(5):528-35
SNF 8906  137442-15-0   *Peptide Fragments Sincalide/*analogs & derivatives. Proc west Pharmacol Soc 1991;34:477-84
SNF 8814  137442-16-1   *Peptide Fragments Sincalide/*analogs & derivatives. Proc West Pharmacol Soc 1991;34:453-9
sincalide, Phe(CH2SO3Na)(2)  0   Sincalide/*analogs & derivatives. Int J Pept Protein Res 1991;37(4):331
JMV 179  119386-87-7 L-Aspartic acid, N-(N-(N-(N-(N-(N-((1,1-dimethylethoxy)carbonyl)-O-sulfo-L-tyrosyl)-L-norleucyl)glycyl)-D-tryptophyl)-L-norleucyl)-, 1-(2-phenylethyl) ester  Sincalide/*analogs & derivatives. Pancreas 1991;6(3):275
JMV 167  120775-49-7 L-alpha-Asparagine, N2-(N-(N-(N-(N-(N-((1,1-dimethylethoxy)carbonyl)-O-sulfo-L-tyrosyl)-L-norleucyl)glycyl)-D-tryptophyl)-L-norleucyl)-N-(2-phenylethyl)  Sincalide/*analogs & derivatives. Pancreas 1991;6(3):275
propionyl CCK octapeptide sulfate  0   Sincalide/*analogs & derivatives. J Pharmacol Exp Ther 1991;257(3):1076
cholecystokinin (26-32), Tyr-Gly-Nle(28,31) phenethyl ester  119400-92-9   *Peptide Fragments Sincalide/*analogs & derivatives. Mol Pharmacol 1991;39(2):150
JMV 170  117829-60-4 L-alpha-Asparagine, N2-(N-(N-(N-(N-(N-((1,1-dimethylethoxy)carbonyl)-O-sulfo-L-tyrosyl)-L-norleucyl)glycyl)-L-tryptophyl)-L-norleucyl)-N-(2-phenylethyl)  Sincalide/*analogs & derivatives. Peptides 1990;11(5):873
SNF 8702  129228-52-0   *Peptide Fragments Sincalide/*analogs & derivatives. J Pharmacol Exp Ther 1990;255(3):1278
sincalide, pGlu  96693-35-5   Pyrrolidonecarboxylic Acid/*analogs & derivatives Sincalide/*analogs & derivatives. Physiol Behav 1990;47(5):911
JMV 236  113137-57-8   *Peptide Fragments Sincalide/*analogs & derivatives. Peptides 1989;10(5):1041
tert-butyloxycarbonylcholecystokinin-8  27220-86-6   Sincalide/*analogs & derivatives. Mol Pharmacol 1989;36(4):647
JMV 182  0   Sincalide/*analogs & derivatives. Am J Physiol 1989;257(4 Pt 1):G594
JMV 81  113282-22-7   Sincalide/*analogs & derivatives. Am J Physiol 1989;257(4 Pt 1):G594
JMV 180  119733-42-5   Sincalide/*analogs & derivatives. Biochim Biophys Acta 1989;1010(2):145
cholecystokinin (26-33), Tyr-Gly-(Nle(28,31),4-NO2-Phe(33))  115136-01-1   *Peptide Fragments Sincalide/*analogs & derivatives. J Biol Chem 1988;263(11):5295
Bolton Hunter-cholecystokinin nonapeptide  117829-67-1   *Succinimides Sincalide/*analogs & derivatives. Am J Physiol 1988;254(2 Pt 1):G176
succinyl-tyrosyl-methionyl-glycyl-tryptophyl-methionyl-aspartyl-phenethylamide  112118-16-8   Sincalide/*analogs & derivatives. Methods Find Exp Clin Pharmacol 1987;9(7):429
cholecystokinin (26-33), I-Tyr-Gly-Nle(28,31)  118688-24-7   *Peptide Fragments Sincalide/*analogs & derivatives. J Biol Chem 1987;262(28):13850
t-butyloxycarbonyl-(sulfo-Tyr)-Met-Gly-Trp-Nle-Asp 2-phenylethyl ester  109525-32-8   Sincalide/*analogs & derivatives. J Biol Chem 1987;262(15):7226
(3-azido-4-hydroxy-5-iodobenzimidyl)-CCK-8  0   *Azides Sincalide/*analogs & derivatives Iodine Radioisotopes. Pancreas 1987;2(1):79
N-(4-(4'-azido-3'-iodophenylazo)benzoyl)-3-aminopropionyl-CCK-8  0   *Azides Sincalide/*analogs & derivatives Iodine Radioisotopes. Pancreas 1987;2(1):79
cholecystokinin (26-33), N-acetyl-norleucine(28,31)  105504-60-7   *Peptide Fragments Sincalide/*analogs & derivatives. Life Sci 1986;39(18):1623
cholecystokinin (26-33), N-alpha-hydroxysulfonyl-Nle(28,31)  105483-63-4   *Peptide Fragments Sincalide/*analogs & derivatives. Life Sci 1986;39(18):1623
cholecystokinin hexapeptide  21163-42-8   *Peptide Fragments *Sincalide. Biopolymers 1985;24(9):1663
cholecystokinin pentapeptide  18917-24-3   *Peptide Fragments *Sincalide. Biopolymers 1985;24(9):1663
cholecystokinin (27-33), t-butyloxycarbonyl  20987-59-1   *Peptide Fragments Sincalide/*analogs & derivatives. Neuropeptides 1986;7(1):1
cholecystokinin (27-33), tert-butyloxycarbonyl-Nle(28,31)  98640-66-5   *Peptide Fragments Sincalide/*analogs & derivatives. Life Sci 1985;37(26):2483
Bolton Hunter-cholecystokinin octapeptide  0   *Succinimides Sincalide/*analogs & derivatives.
Pharma Action Indicators and Reagents 		J Pharmacol Exp Ther 1985;232(3):775
cholecystokinin (26-33)  80980-81-0   Sincalide/*analogs & derivatives. Am J Physiol 1985;248(1 Pt 1):G98
cholecystokinin (26-32)  0   Sincalide/*analogs & derivatives. Am J Physiol 1984;246(3 pt 1):G292
cholecystokinin octapeptide, des-NH2-Tyr  79672-08-5 Caerulein, 1-de(5-oxo-L-proline)-2-de-L-glutamine-3-(N-(3-(4-hydroxy-3-iodophenyl)-1-oxopropyl)-L-aspartic acid)-5-L-methionine  Sincalide/*analogs & derivatives. J Biol Chem 1981;256(23):12417
acetylcholecystokinin C-terminal heptapeptide  77275-51-5 L-Phenylalaninamide, N-acetyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-, disodium salt  *Peptide Fragments Sincalide/*analogs & derivatives. Int J Pept Protein Res 1980;16(5):402
cholecystokinin (27-33)  20988-64-1   *Peptide Fragments *Sincalide. Biochim Biophys Acta 1980;630(3):323
desaminopancreozymin octapeptide  67436-51-5 L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl  Sincalide/*analogs & derivatives. Pharmazie 34(5-6):346;1979
cholecystokinin-pancreozymin, Tyr(27)  60383-26-8   Sincalide/*analogs & derivatives. Gastroenterology 72:793;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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