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Glycine Hydroxymethyltransferase

More information in Books or onNLM PubMed
Definition: A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the reaction of glycine with acetaldehyde to form L-threonine. EC 2.1.2.1.      Other names Threonine Aldolase; Serine Transhydroxymethylase; Serine Hydroxymethyltransferase; Serine Hydroxymethylase; Serine Aldolase; Transhydroxymethylase, Serine; Hydroxymethyltransferase, Serine; Hydroxymethyltransferase, Glycine; Hydroxymethylase, Serine; Aldolase, Threonine; Aldolase, Allothreonine; Allothreonine Aldolase; Aldolase, Serine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Shmt1 protein, mouse  EC 2.1.2.1   *Glycine Hydroxymethyltransferase. Cancer Res. 2011 Mar 15;71(6):2098-107
SHMT1 protein, human  EC 2.1.2.1   *Glycine Hydroxymethyltransferase. Gene 1998 Apr 14;210(2):315-24
SHM2 protein, Arabidopsis  EC 2.1.2.1   *Glycine Hydroxymethyltransferase *Arabidopsis Proteins Mitochondrial Proteins. Plant Physiol 2006 Jan;140(1):59-66
SHM1 protein, Arabidopsis  EC 2.1.2.1   *Glycine Hydroxymethyltransferase *Arabidopsis Proteins Mitochondrial Proteins. Plant Physiol 2006 Jan;140(1):59-66
SHMT1 protein, Arabidopsis  EC 2.1.2.1   *Glycine Hydroxymethyltransferase *Arabidopsis Proteins. Plant J 2005 Feb;41(3):386-99

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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