encyclopedia of medical concepts
ψ 

Saccharopine Dehydrogenases

More information in Books or onNLM PubMed
Definition: Amine oxidoreductases that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS.  /defic: consider also HYPERLYSINEMIAS   
See Also Hyperlysinemias 		Other names Reductase, Lysine-Ketoglutarate; Reductase, Lysine-2-Oxoglutarate; Lysine Ketoglutarate Reductase; Lysine 2 Oxoglutarate Reductase; Dehydrogenases, Saccharopine; Saccharopine Dehydrogenase (NADP+, L-Lysine Formin; Saccharopine Dehydrogenase (NADP+, L-Glutamate For; Saccharopine Dehydrogenase (NAD+, L-Lysine Forming; Saccharopine Dehydrogenase (NAD+, L-Glutamate Form; Lysine-Ketoglutarate Reductase; Lysine-2-Oxoglutarate Reductase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Saccharopinuria  0   *Hyperlysinemias Saccharopine Dehydrogenases/deficiency.
Aass protein, mouse  EC 1.5.1.-   *Saccharopine Dehydrogenases. J Nutr 2008 Nov;138(11):2143-7
AASS protein, human  EC 1.5.1.-   *Saccharopine Dehydrogenases Hyperlysinemias. J Biol Chem 1984;259(19):11643
saccharopine dehydrogenase (NADP, L-glutamate-forming)  EC 1.5.1.10   *Saccharopine Dehydrogenases. J Bacteriol 1984;159(1):429
saccharopine dehydrogenase (NADP+, lysine-forming)  EC 1.5.1.8   *Saccharopine Dehydrogenases. Biochim Biophys Acta 1980;633(3):310

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy