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Protein O-Methyltransferase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the transfer of methyl groups from S-adenosylmethionine to free carboxyl groups of a protein molecule forming methyl esters. EC 2.1.1.-.  do not confuse with PROTEIN METHYLTRANSFERASES; DF: note short X ref   
Examples Protein D-Aspartate-L-Isoaspartate Methyltransferase 		Other names Protein Methyltransferase II; Protein Methylase II; Protein Carboxylmethyltransferase; Transferase, S-Adenosylmethionine-Protein Carboxym; S Adenosylmethionine Protein O Methyltransferase; S Adenosylmethionine Protein Carboxymethyltransfer; S Adenosylmethionine Protein Carboxymethyl Transfe; Protein O-Methyltransferase, S-Adenosylmethionine; Protein O Methyltransferase; Protein O Carboxymethyltransferase; Protein Carboxymethyltransferase, S-Adenosylmethio; Protein Carboxyl Methylase; O-Methyltransferase, S-Adenosylmethionine Protein; O-Methyltransferase, Protein; O-Carboxymethyltransferase, Protein; Methyltransferase II, Protein; Methylase II, Protein; Carboxymethyltransferase, S-Adenosylmethionine Pro; Carboxymethylase, Protein; Carboxymethyl Transferase, S-Adenosylmethionine-Pr
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NovP protein, Streptomyces  EC 2.1.1.-.   *Protein O-Methyltransferase. Acta Crystallogr D Biol Crystallogr 2007 Oct;63(Pt 10):1069-74
leucine carboxyl methyltransferase-1, human  EC 2.1.1.-   Protein O-Methyltransferase. J Biol Chem 2007 Oct 19;282(42):30974-84
C-terminal leucine protein methyltransferase  EC 2.1.1.-   *Protein O-Methyltransferase. J Biol Chem 1994 Jan 21;269(3):1981-4
5'-methylthioadenosine  2457-80-9   *Deoxyadenosines *Thionucleosides Protein O-Methyltransferase/antagonists & inhibitors.
Pharma Action Antimalarials ; Enzyme Inhibitors 		Biochem Biophys Res Commun 73(3):600;1976; Biochem Biophys Res Commun 78(4):1273;1977; Biochem Biophys Res Commun 81:1398;1978; Biochim Biophys Acta 1979;588(3):294; Biochim Biophys Acta 320(2):357;1973; Cell Immunol 1980;49(1):26; Experientia 33(12):1559;1977; FEBS Lett 99(2):247;1979; FEBS Lett 99(2):343;1979; Int J Biochem 1979;10(11):919; J Nutr 107(10):1927;1977; J Nutr Sci Vitaminol (Tokyo) 22(2):89;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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