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Propafenone

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Definition: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.     
Pharmacological Action Anti-Arrhythmia Agents
Other names SA 79; Hydrochloride, Propafenone; TAD Brand of Propafenone Hydrochloride; SA-79; Rytmonorm; Rytmogenat; Rytmo-Puren; Q-Pharm Brand of Propafenone Hydrochloride; Propafenone, (S)-Isomer; Propafenone, (R)-Isomer; Propafenone, (+-)-Isomer; Propamerck; Propafenone Hydrochloride, (S)-Isomer; Propafenone Hydrochloride, (R)-Isomer; Propafenone Hydrochloride; Propafenon Minden; Propafenon Hexal; Propafenon AL; Prolecofen; PintoformDrugs* : PROPAFENONE HYDROCHLORIDE; RYTHMOL SR; RYTHMOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-hydroxydiprafenone  127848-69-5   Propafenone/*analogs & derivatives. Pharmazie 1994 Jan;49(1):38-41
LG 6-102  132798-30-2 1-Propanone, 1-(2-(2-methoxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride  Propafenone/*analogs & derivatives. Arzneimiteelforschung 1991;41(2):119
LG 6-101  132798-26-6 1-Propanone, 1-(3-(2-methoxy-3-((2-methylpropyl)amino)propoxy)-4-methyl-2-thienyl)-3-phenyl-, hydrochloride  Propafenone/*analogs & derivatives. Arzneimittelforschung 1991;41(2):119
5-hydroxy-4-methoxypropafenone  102059-09-6   Propafenone/*analogs & derivatives. Eur J Clin Pharmacol 1990;38(5):509
diprafenone  81447-80-5   Propafenone/*analogs & derivatives.
Pharma Action Anti-Arrhythmia Agents
Arzneimittelforschung 1985;35(9):1387
N-depropylpropafenone  86383-21-3   Propafenone/*analogs & derivatives. Clin Pharmacol Ther 1985;37(6):610
5-hydroxypropafenone  86384-10-3   Propafenone/*analogs & derivatives.
Pharma Action Adrenergic beta-Antagonists ; Anti-Arrhythmia Agents
Arzneimittlforsch 1984;34(11):1455
butafenone  85414-48-8 1-Propanone, 1-(2-(3-(butylamino)-2-hydroxypropoxy)phenyl)-3-phenyl  Propafenone/*analogs & derivatives. Pflugers Arch 1983;396(3):199
SA 76  85414-47-7   Propafenone/*analogs & derivatives. Pflugers Arch 1983;396(3):199
etafenone  90-54-0 2'-(2-(diethylamino)ethoxy)- 3-phenylpropiophenone  Propafenone/*analogs & derivatives.
Pharma Action Vasodilator Agents
Arzneim Forsch 25(1):31;1975; Arzneim Forsch 25(9):1400;1975; Arzneim Forsch 26(12):2158;1976; Clin Ther 74(4):337;1975; Kardiologiia 18(3):43;1978; Kardiologiia 18(3):48;1978; Kokyu To Junkan 1979;27(11):1203; Med Klin 66(46):1564;1971; Resp Circ 26(8):767;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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