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Proadifen

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Definition: An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.  D25-26 qualif   
Pharmacological Action Enzyme Inhibitors 		Other names Propyladiphenin; SKF525A; SKF 525 A; SK525A; SK&F525A; SK&F 525 A; SK 525A; Hydrochloride, Proadifen; Acetate, Diethylaminoethyldiphenylpropyl; SKF-525A; SKF-525-A; SK-525A; SK&F-525-A; Proadifen Hydrochloride; Diethylaminoethyldiphenylpropyl Acetate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
meproadifen mustard  105555-57-5   Proadifen/*analogs & derivatives. J Biol Chem 1986;261(29):13727
SK&F 8742A  13062-02-7   Proadifen/*analogs & derivatives. Biochem Pharmacol 1980;29(19):2577
meproadifen  70147-13-6 Ethanaminium, N,N-diethyl-N-methyl-2-((1-oxo-2,2-diphenylpentyl)oxy)  Proadifen/*analogs & derivatives. Proc Natl Acad Sci USA 76(2):690;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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