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Prions

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Definition: Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.  /pathogen permitted   
Examples PrPC Proteins; PrPSc Proteins 		Other names Prion Proteins; PrP Proteins; Mink Encephalopathy Virus; Encephalopathy Virus, Mink
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PQN-47 protein, C elegans  0   *Prions *Caenorhabditis elegans Proteins. Dev Biol. 2011 Dec 15;360(2):297-309
New1 protein, S cerevisiae  0   *Prions *Saccharomyces cerevisiae Proteins. Genes Cells 2011 May;16(5):545-56
prion protein (76-114), human  0   *Peptide Fragments *Prions. Inorg Chem. 2009 May 4;48(9):4239-50
prion protein (23-98)  0   *Peptide Fragments *Prions. Protein Pept Lett 2009;16(1):91-6
prion protein (131-188)  0   *Peptide Fragments *Prions. Arch Virol 2007;152(3):603-9
prion protein (91-231), human  0   *Peptide Fragments *Prions. Biochim Biophys Acta 1999 Apr 12;1431(1):1-13
Prnp protein, mouse  0   *Prions.
PRNP protein, human  0   *Prions.
prion protein (125-228), human  0   *Peptide Fragments *Prions. Proteins 2006 Jul 1;64(1):167-77
prion protein (214-226)  0   *Peptide Fragments *Prions. Biochem Biophys Res Commun 2006 Jun 16;344(4):1320-6
prion protein (90-231)  0   *Peptide Fragments *Prions. Biochemistry 2005 Dec 6;44(48):15880-8
prion protein (198-227)  0   *Peptide Fragments *Prions. Int J Immunopathol Pharmacol 2005 Jan-Mar;18(1):95-112
PRND protein, human  0   *Prions GPI-Linked Proteins.
prion protein (113-132)  0   *Peptide Fragments *Prions. Biochem Biophys Res Commun 2005 Mar 4;328(1):14-9
prion protein (23-110)  0   *Peptide Fragments *Prions. J Thromb Haemost 2004 Jun;2(6):962-8
prion protein (82-146)  0   *Prions *Peptide Fragments. Am J Physiol Cell Physiol 2003 Oct;285(4):C862-72
prion protein (60-67)  0   *Peptide Fragments *Prions. J Neurochem 2003 May;85(3):709-16
prion protein (59-91)  0   *Peptide Fragments *Prions. J Neurochem 2003 May;85(3):709-16
miniprion protein PrP106, mouse  0   *Prions Recombinant Proteins. J Biol Chem 2002 Aug 30;277(35):31327-34
Sup35 protein, Candida albicans  0   *Fungal Proteins *Prions. Microbiology 2002 Apr;148(Pt 4):1049-60
Prnp protein, leucyl(101), mouse  0   *Prions Recombinant Proteins. EMBO J 2001 Sep 17;20(18):5070-8
prion protein (23-231)  0   *Peptide Fragments *Prions. J Biol Chem 2001 Jan 26;276(4):2427-31
prion protein (105-132)  0   *Peptide Fragments *Prions. Neurobiol Dis. 2000 Dec;7(6 Pt B):644-56
prion protein (127-147)  0   *Peptide Fragments *Prions. J Neurochem 2000 Dec;75(6):2536-45
prion protein (118-135)  0   *Peptide Fragments *Prions. J Neurochem 2000 Dec;75(6):2298-308
RNQ1 protein, S cerevisiae  0   *Prions *Saccharomyces cerevisiae Proteins. Mol Cell 2000 Jan;5(1):163-72
Prnd protein, mouse  0   *Prions GPI-Linked Proteins. J Mol Biol 1999 Oct1;292(4):797-817
prion protein (143-158)  0   *Peptide Fragments *Prions. Biopolymers 1999;51(2):145-52
(ctm)PrP  0   *Prions. Science 1998 Feb;279(5352);827-34
prion protein (121-231)  0   *Peptide Fragments *Prions. Nature 1996 Jul 11;382(6587):180-2
prion protein (106-126)  0   *Peptide Fragments *Prions. Biochem Biophys Res Commun 1993 Aug 16;194(3):1380-6
URE2 protein, S cerevisiae  EC 1.11.1.9   *Glutathione Peroxidase *Prions *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1991;11(2):822

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